Vigilance, anxiety, epileptic activity, and muscle tone can be modulated by drugs acting at
the benzodiazepine (BZ) site of gamma-aminobutyric acid type A (GABAA) receptors. In vivo, …

Despite several therapeutic advances, malignant melanoma still remains a fatal disease for
which novel and long-term curative treatments are needed. The successful development of …

… If glass fragments are supposed to fail within 1 m distance from the opening, the threat is
rated as ‘very low’; when the fragments fly higher than 0.6 m at 3 m distance, the hazard level is …

Resistance to therapy and lack of curative treatments for metastatic breast cancer suggest
that current therapies may be missing the subpopulation of chemoresistant and radioresistant …

… in the presence of 150 M of a MyD88 homodimerization inhibitory peptide or of a control
peptide (Imgenex, San Diego, CA, USA); in the presence of bacterial ligands Pam3CSK4 (a …

… Later, as Ten-m mutants failed to display a pair-rule phenotype, a different role was
proposed and Ten-m/Odz genes were demonstrated to code for transmembrane proteins with a …

Alteration in RNA metabolism, concerning both coding and long non-coding RNAs (lncRNAs),
may play an important role in Amyotrophic Lateral Sclerosis (ALS) pathogenesis. In this …

Mesenchymal stromal cells (MSCs) are adult, multipotent cells of mesodermal origin
representing the progenitors of all stromal tissues. MSCs possess significant and broad …

Background Reproducibility of a research is a key element in the modern science and it is
mandatory for any industrial application. It represents the ability of replicating an experiment …

Identifying biomarkers is essential for early diagnosis of neurodegenerative diseases (NDs).
Large (LEVs) and small extracellular vesicles (SEVs) are extracellular vesicles (EVs) of …