A roadmap to increase diversity in genomic studies
Two decades ago, the sequence of the first human genome was published. Since then,
advances in genome technologies have resulted in whole-genome sequencing and microarray-…
advances in genome technologies have resulted in whole-genome sequencing and microarray-…
[HTML][HTML] An international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, CRP, and clozapine levels
…, A Wilkowska, WJ Cubała, M Ayub… - …, 2022 - thieme-connect.com
This international guideline proposes improving clozapine package inserts worldwide by
using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest …
using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest …
[HTML][HTML] The genetic basis of non-syndromic intellectual disability: a review
L Kaufman, M Ayub, JB Vincent - Journal of neurodevelopmental disorders, 2010 - Springer
Intellectual disability (ID), also referred to as mental retardation (MR), is frequently the result
of genetic mutation. Where ID is present together with additional clinical symptoms or …
of genetic mutation. Where ID is present together with additional clinical symptoms or …
[HTML][HTML] Brain charts for the human lifespan
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …
and clinical studies of the human brain. However, no reference standards currently exist to …
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
…, O Pietiläinen, SS Gerety, M Ayub, M Blyth… - Nature …, 2016 - nature.com
By analyzing the whole-exome sequences of 4,264 schizophrenia cases, 9,343 controls
and 1,077 trios, we identified a genome-wide significant association between rare loss-of-…
and 1,077 trios, we identified a genome-wide significant association between rare loss-of-…
Alterations of the CIB2 calcium-and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48
Sensorineural hearing loss is genetically heterogeneous. Here, we report that mutations in
CIB2, which encodes a calcium- and integrin-binding protein, are associated with …
CIB2, which encodes a calcium- and integrin-binding protein, are associated with …
Antimicrobial activity of Calendula officinalis petal extracts against fungi, as well as Gram-negative and Gram-positive clinical pathogens
The aim of the present study was to assess the antimicrobial activity of methanol and ethanol
extracts of pot marigold (Calendula officinalis) petals against clinical pathogens. The …
extracts of pot marigold (Calendula officinalis) petals against clinical pathogens. The …
[PDF][PDF] Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability
Causes of autosomal-recessive intellectual disability (ID) have, until very recently, been
under researched because of the high degree of genetic heterogeneity. However, now that …
under researched because of the high degree of genetic heterogeneity. However, now that …
Screen use and mental health symptoms in Canadian children and youth during the COVID-19 pandemic
Importance Longitudinal research on specific forms of electronic screen use and mental
health symptoms in children and youth during COVID-19 is minimal. Understanding the …
health symptoms in children and youth during COVID-19 is minimal. Understanding the …
[PDF][PDF] Response of maize (Zea mays L.) fodder to different levels of nitrogen and phosphorus
M Ayub, MA Nadeem, MS Sharar… - Asian Journal of Plant …, 2002 - researchgate.net
A field experiment vvas conducted to evaluate the effect of different combination of nitrogen
and phosphorus on the fodder yield and quality of maize (Zea mays L.). The maize cultivar …
and phosphorus on the fodder yield and quality of maize (Zea mays L.). The maize cultivar …