User profiles for M. Barakovic
Muhamed BarakovicPharma Research and Early Development - Roche Verified email at roche.com Cited by 2813 |
[HTML][HTML] The challenge of mapping the human connectome based on diffusion tractography
…, S Alexander, D Romascano, M Barakovic… - Nature …, 2017 - nature.com
Tractography based on non-invasive diffusion imaging is central to the study of human brain
connectivity. To date, the approach has not been systematically validated in ground truth …
connectivity. To date, the approach has not been systematically validated in ground truth …
[HTML][HTML] The functional characterization of callosal connections
The brain operates through the synaptic interaction of distant neurons within flexible, often
heterogeneous, distributed systems. Histological studies have detailed the connections …
heterogeneous, distributed systems. Histological studies have detailed the connections …
Tractostorm: The what, why, and how of tractography dissection reproducibility
…, M Chamberland, M Barakovic… - Human brain …, 2020 - Wiley Online Library
Investigative studies of white matter (WM) brain structures using diffusion MRI (dMRI)
tractography frequently require manual WM bundle segmentation, often called “virtual dissection.” …
tractography frequently require manual WM bundle segmentation, often called “virtual dissection.” …
Limits to anatomical accuracy of diffusion tractography using modern approaches
Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the brain,
with a range of applications in both clinical and basic neuroscience. Despite widespread …
with a range of applications in both clinical and basic neuroscience. Despite widespread …
Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study
…, J Kuhle, S Aeschbacher, M Barakovic… - The Lancet …, 2022 - thelancet.com
… Example 1, at 30 years and a BMI of 25 kg/m 2 , shows sNfL of 9·5 pg/mL (95th percentile)
and Z score of more than 1·5 (exact value 1·64, as calculated by the sNfL app), and the …
and Z score of more than 1·5 (exact value 1·64, as calculated by the sNfL app), and the …
[HTML][HTML] Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?
White matter bundle segmentation using diffusion MRI fiber tractography has become the
method of choice to identify white matter fiber pathways in vivo in human brains. However, like …
method of choice to identify white matter fiber pathways in vivo in human brains. However, like …
Association of brain atrophy with disease progression independent of relapse activity in patients with relapsing multiple sclerosis
A Cagol, S Schaedelin, M Barakovic, P Benkert… - JAMA …, 2022 - jamanetwork.com
Importance The mechanisms driving neurodegeneration and brain atrophy in relapsing
multiple sclerosis (RMS) are not completely understood. Objective To determine whether …
multiple sclerosis (RMS) are not completely understood. Objective To determine whether …
A new advanced MRI biomarker for remyelinated lesions in multiple sclerosis
…, PJ Lu, E Bahn, M Weigel, M Barakovic… - Annals of …, 2022 - Wiley Online Library
Objectives Neuropathological studies have shown that multiple sclerosis (MS) lesions are
heterogeneous in terms of myelin/axon damage and repair as well as iron content. However, it …
heterogeneous in terms of myelin/axon damage and repair as well as iron content. However, it …
Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging
… (M and N) MWF and NDI were not different between RRMS and PMS. (O) NDI-MWF scatter
… (M and N) MWF and NDI were not different between RRMS and PMS. (O) NDI-MWF scatter …
… (M and N) MWF and NDI were not different between RRMS and PMS. (O) NDI-MWF scatter …
Serum glial fibrillary acidic protein compared with neurofilament light chain as a biomarker for disease progression in multiple sclerosis
…, L Melie-Garcia, A Cagol, M Barakovic… - JAMA …, 2023 - jamanetwork.com
Importance There is a lack of validated biomarkers for disability progression independent of
relapse activity (PIRA) in multiple sclerosis (MS). Objective To determine how serum glial …
relapse activity (PIRA) in multiple sclerosis (MS). Objective To determine how serum glial …