… Heterozygous mice that are agouti carry a methylated A vy allele ( m A vy ), which is
effectively a … Homozygous mice with two methylated A vy alleles ( m A vy / m A vy ) are agouti. …

Variations in sample quality are frequently encountered in small RNA-sequencing
experiments, and pose a major challenge in a differential expression analysis. Removal of high …

X-chromosome inactivation is the mammalian dosage compensation mechanism by which
transcription of X-linked genes is equalized between females and males. In an N-ethyl-N-…

Much of what we know about the role of epigenetics in the determination of phenotype has
come from studies of inbred mice. Some unusual expression patterns arising from …

Transcriptional control is dependent on a vast network of epigenetic modifications. One
epigenetic mark of particular interest is tri-methylation of lysine 27 on histone H3 (H3K27me3), …

There is increasing evidence in both plants and animals that epigenetic marks are not always
cleared between generations. Incomplete erasure at genes associated with a measurable …

It has very recently become clear that the epigenetic modifier SMCHD1 has a role in two
distinct disorders: facioscapulohumoral muscular dystrophy (FSHD) and Bosma arhinia and …

We have developed a sensitized screen to identify genes involved in gene silencing, using
random N-ethyl-N-nitrosourea mutagenesis on mice carrying a variegating GFP transgene. …

There is increasing evidence that epigenetic information can be inherited across generations
in mammals, despite extensive reprogramming both in the gametes and in the early …

… Marnie E Blewitt , Marnie E Blewitt … Shian Su, Charity W Law, Casey Ah-Cann, Marie-Liesse
Asselin-Labat, Marnie E Blewitt, Matthew E Ritchie, Glimma: interactive graphics for gene …