The 2022 report of the Lancet Countdown is published as the world confronts profound and
concurrent systemic shocks. Countries and health systems continue to contend with the …

Background Shortages of human resources for health (HRH) have severely hampered the
rollout of antiretroviral therapy (ART) in sub-Saharan Africa. Current rollout models are …

In the past few decades, major public health advances have happened in Europe, with drastic
decreases in premature mortality and a life expectancy increase of almost 9 years since …

The trafficking of circulating stem and progenitor cells to areas of tissue damage is poorly
understood. The chemokine stromal cell–derived factor-1 (SDF-1 or CXCL12) mediates …

Objective To examine the effects of intranasal insulin administration on cognition, function,
cerebral glucose metabolism, and cerebrospinal fluid biomarkers in adults with amnestic mild …

The most recent IPCC assessment has shown an important role for negative emissions
technologies (NETs) in limiting global warming to 2 C cost-effectively. However, a bottom-up, …

Paradyn is a tool for measuring the performance of large-scale parallel programs. Our goal
in designing a new performance tool was to provide detailed, flexible performance …

Diminished production of vascular endothelial growth factor (VEGF) and decreased angiogenesis
are thought to contribute to impaired tissue repair in diabetic patients. We examined …

Background Emicizumab (ACE910) bridges activated factor IX and factor X to restore the
function of activated factor VIII, which is deficient in persons with hemophilia A. This phase 3, …

Patellofemoral pain affects physically active and sedentary individuals, accounting for 11–17%
of knee pain presentations to general practice 1 2 and 25–40% of all knee problems …