User profiles for M. Diard
Médéric RJ DiardSNSF Assistant Professor, Basel University Biozentrum Verified email at unibas.ch Cited by 4606 |
Evolutionary causes and consequences of bacterial antibiotic persistence
… Additionally, it was recently shown that a host factor, SLC11a1, which restricts systemic
growth of pathogens such as M. tuberculosis and S. Typhimurium by depleting local Mg 2+ …
growth of pathogens such as M. tuberculosis and S. Typhimurium by depleting local Mg 2+ …
The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune …
… enterica serovar Typhi: bacteria invade the mucosa via M-cells, colonize Peyer′s patches
… We are grateful to the members of the Hardt lab for in depth discussions and to M. Rohde, P. …
… We are grateful to the members of the Hardt lab for in depth discussions and to M. Rohde, P. …
Evolution of bacterial virulence
Bacterial virulence is highly dynamic and context-dependent. For this reason, it is challenging
to predict how molecular changes affect the growth of a pathogen in a host and its spread …
to predict how molecular changes affect the growth of a pathogen in a host and its spread …
[HTML][HTML] Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths
The Escherichia coli species represents one of the best-studied model organisms, but also
encompasses a variety of commensal and pathogenic strains that diversify by high rates of …
encompasses a variety of commensal and pathogenic strains that diversify by high rates of …
[PDF][PDF] Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa
…, AA Müller, B Felmy, T Dolowschiak, M Diard… - Cell host & …, 2014 - cell.com
The gut mucosal epithelium separates the host from the microbiota, but enteropathogens such
as Salmonella Typhimurium (S.Tm) can invade and breach this barrier. Defenses against …
as Salmonella Typhimurium (S.Tm) can invade and breach this barrier. Defenses against …
High-avidity IgA protects the intestine by enchaining growing bacteria
Vaccine-induced high-avidity IgA can protect against bacterial enteropathogens by directly
neutralizing virulence factors or by poorly defined mechanisms that physically impede …
neutralizing virulence factors or by poorly defined mechanisms that physically impede …
Stabilization of cooperative virulence by the expression of an avirulent phenotype
… For infection, bacteria were grown in 0.3 M NaCl LB medium supplemented with the appropriate
antibiotic for 12 h at 37 C, and subcultured for 4 h in the same medium without antibiotic …
antibiotic for 12 h at 37 C, and subcultured for 4 h in the same medium without antibiotic …
[HTML][HTML] Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation
…, IA Vizcarra, R Peña-Miller, N Stocker, M Diard… - PLoS …, 2014 - journals.plos.org
… M Diard was supported in part by the Fondation pour la Recherche Medicale. The funders
had no role in study design, data collection and analysis, decision to publish, or preparation of …
had no role in study design, data collection and analysis, decision to publish, or preparation of …
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut
The emergence of antibiotic-resistant bacteria through mutations or the acquisition of
genetic material such as resistance plasmids represents a major public health issue 1 , 2 . …
genetic material such as resistance plasmids represents a major public health issue 1 , 2 . …
Inflammation boosts bacteriophage transfer between Salmonella spp.
Bacteriophage transfer (lysogenic conversion) promotes bacterial virulence evolution. There
is limited understanding of the factors that determine lysogenic conversion dynamics within …
is limited understanding of the factors that determine lysogenic conversion dynamics within …