Although hatching from eggs is fundamental for nematode biology it remains poorly understood.
For animal-parasitic nematodes in particular, advancement has been slow since the …

Organoids are multicellular culture systems that replicate tissue architecture and function,
and are increasingly used as models of viral, bacterial, and protozoan infections. Organoids …

… Next, we determined whether infection with the attenuated vaccine strain M. bovis BCG …
-1β in macrophages and this propensity was apparently lost during attenuation of M. bovis BCG. …

Lung granulomas develop upon Mycobacterium tuberculosis (Mtb) infection as a hallmark
of human tuberculosis (TB). They are structured aggregates consisting mainly of Mtb-infected …

Enteric fever, caused by Salmonella enterica serovar Typhi, is an important public health
problem in resource-limited settings and, despite decades of research, human responses to the …

Regulatory T cells (T reg cells) are characterized by the expression of the forkhead lineage-specific
transcription factor Foxp3, and their main function is to suppress T cells. While …

The probabilistic expression of cytokine genes in differentiated T helper (Th) cell populations
remains ill defined. By single-cell analyses and mathematical modeling, we show that one …

… Duque-Correa, and Marcus Clauss performed the literature research. Annika Avedik and …
Duque-Correa was supported by a grant of the Swiss National Science Foundation (…

By developing a high-density murine immunophenotyping platform compatible with high-throughput
genetic screening, we have established profound contributions of genetics and …

Whole-genome sequencing is being rapidly applied to the study of helminth genomes, including
de novo genome assembly, population genetics, and diagnostic applications. Although …