User profiles for M. Elkabets
Moshe ElkabetsBen-Gurion University of the Negev Verified email at bgu.ac.il Cited by 4755 |
The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions
RN Apte, S Dotan, M Elkabets, MR White… - Cancer and Metastasis …, 2006 - Springer
Interleukin-1 (IL-1) includes a family of closely related genes; the two major agonistic proteins,
IL-1α and IL-1β, are pleiotropic and affect mainly inflammation, immunity and hemopoiesis…
IL-1α and IL-1β, are pleiotropic and affect mainly inflammation, immunity and hemopoiesis…
Effects of micro-environment-and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour–host interactions
…, Y Krelin, X Song, S Dotan, E Recih, M Elkabets… - European journal of …, 2006 - Elsevier
Interleukin-1 (IL-1) comprises a family of closely related genes; the two major agonistic
proteins, IL-1α and IL-1β, are pleiotropic and affect mainly inflammation, immunity and …
proteins, IL-1α and IL-1β, are pleiotropic and affect mainly inflammation, immunity and …
Molecular pathways: AXL, a membrane receptor mediator of resistance to therapy
M Scaltriti, M Elkabets, J Baselga - Clinical Cancer Research, 2016 - AACR
AXL is a tyrosine kinase membrane receptor that signals via PI3K, MAPK, and protein kinase
C (PKC), among other pathways. AXL has oncogenic potential and interacts with other …
C (PKC), among other pathways. AXL has oncogenic potential and interacts with other …
Interleukin-1β–Driven inflammation promotes the development and invasiveness of chemical carcinogen–Induced tumors
…, S Dotan, M Elkabets, E Reich, M Fogel, M Huszar… - Cancer research, 2007 - AACR
The role of microenvironment interleukin 1 (IL-1) on 3-methylcholanthrene (3-MCA)–induced
carcinogenesis was assessed in IL-1–deficient mice, ie, IL-1β −/− , IL-1α −/− , IL-1α/β −/− (…
carcinogenesis was assessed in IL-1–deficient mice, ie, IL-1β −/− , IL-1α −/− , IL-1α/β −/− (…
[PDF][PDF] AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas
Phosphoinositide-3-kinase (PI3K)-α inhibitors have shown clinical activity in squamous cell
carcinomas (SCCs) of head and neck (H&N) bearing PIK3CA mutations or amplification. …
carcinomas (SCCs) of head and neck (H&N) bearing PIK3CA mutations or amplification. …
mTORC1 Inhibition Is Required for Sensitivity to PI3K p110α Inhibitors in PIK3CA-Mutant Breast Cancer
M Elkabets, S Vora, D Juric, N Morse… - Science translational …, 2013 - science.org
… For each gene K, we let {k 1 , k 2 , …, k m } be the set of percent knockdowns for the shRNAs
targeting K and let k max denote the maximum percent knockdown in this set. The weights …
targeting K and let k max denote the maximum percent knockdown in this set. The weights …
IL‐1β regulates a novel myeloid‐derived suppressor cell subset that impairs NK cell development and function
M Elkabets, VSG Ribeiro, CA Dinarello… - European journal of …, 2010 - Wiley Online Library
… Moshe Elkabets was supported by the Chateaubriand scientific pre- and post-doctorate
fellowships 2007-2008, Nehemia-Lev-Zion excellent Ph.D scholarship and ISEF Foundation. …
fellowships 2007-2008, Nehemia-Lev-Zion excellent Ph.D scholarship and ISEF Foundation. …
[HTML][HTML] Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice
M Elkabets, AM Gifford, C Scheel… - The Journal of …, 2011 - Am Soc Clin Investig
Systemic instigation is a process by which endocrine signals sent from certain tumors (instigators)
stimulate BM cells (BMCs), which are mobilized into the circulation and subsequently …
stimulate BM cells (BMCs), which are mobilized into the circulation and subsequently …
PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D
Activating mutations in PIK3CA, the gene encoding phosphoinositide-(3)-kinase α (PI3Kα),
are frequently found in estrogen receptor (ER)–positive breast cancer. PI3Kα inhibitors, now …
are frequently found in estrogen receptor (ER)–positive breast cancer. PI3Kα inhibitors, now …
P-selectin is a nanotherapeutic delivery target in the tumor microenvironment
Disseminated tumors are poorly accessible to nanoscale drug delivery systems because of
the vascular barrier, which attenuates extravasation at the tumor site. We investigated P-…
the vascular barrier, which attenuates extravasation at the tumor site. We investigated P-…