Peptide-receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogs such
as octreotide is an effective therapy against neuroendocrine tumors. Other radiolabeled …

Nuclear medicine imaging procedures play an important role in the assessment of
inflammatory diseases. With the advent of 3-dimensional anatomic imaging, there has been a …

Prostate cancer (PCa) is the most common malignancy in men worldwide, leading to substantial
morbidity and mortality. At present, imaging of PCa has become increasingly important …

Layering of neurons in the cerebral cortex and cerebellum requires Reelin, an extracellular
matrix protein, and mammalian Disabled (mDab1), a cytosolic protein that activates tyrosine …

Titin is a giant vertebrate striated muscle protein with critical importance for myofibril elasticity
and structural integrity. We show here that the complete sequence of the human titin gene …

sorLA (sorting protein-related receptor) is a type-1 membrane protein of unknown function
that is expressed in neurons. Its homology to sorting receptors that shuttle between the …

Alternative splicing has a major role in cardiac adaptive responses, as exemplified by the
isoform switch of the sarcomeric protein titin, which adjusts ventricular filling. By positional …

… After hybridization, slides were washed in 5× SSC, 100 mm DTT at 65 C for 30 min, and
covered with K.5 nuclear emulsion (Ilford) before exposure at 4 C for 21 to 35 days. …

Vascular smooth muscle cell (SMC) proliferation and migration are important events in the
development of atherosclerosis. The low-density lipoprotein receptor–related protein (LRP1) …

The recent discovery of heterozygous human mutations that truncate full-length titin (TTN, an
abundant structural, sensory, and signaling filament in muscle) as a common cause of end-…