Species introduced through human-related activities beyond their native range, termed alien
species, have various impacts worldwide. The IUCN Environmental Impact Classification …

Background Treatment of adults with autoimmune thrombocytopenic purpura (AITP) is
based more on individual experience than on results of controlled studies. We compared …

The ancient cratered terrain of the southern highlands of Mars is thought to hold clues to the
planet’s early differentiation 1 , 2 , but until now no meteoritic regolith breccias have been …

We investigated reactive oxygen species (ROS) involvement in polymorphonuclear neutrophilic
leukocyte (neutrophil) apoptosis triggering. Neutrophils were incubated with xanthine …

In skeletal muscle, nebulin stabilizes and regulates the length of thin filaments, but the
underlying mechanism remains nebulous. In this work, we used cryo–electron tomography and …

We report the cytogenetic results obtained in 81 multiple mye-loma (MM) patients with abnormal
karyotypes. Most karyotypes were complex with numerical and structural abnormalities …

Sarcomeres are force-generating and load-bearing devices of muscles. A precise molecular
picture of how sarcomeres are built underpins understanding their role in health and …

… The combined reconstructions comprise the M band, P zone and C zone and reveal the
positions of M-band proteins together with the first 31 myosin layers, encompassing 6 titin …

Structural biology studies inside cells and tissues require methods to thin vitrified specimens
to electron transparency. Until now, focused ion beams based on gallium have been used. …

Vesicular nucleo-cytoplasmic transport is becoming recognized as a general cellular
mechanism for translocation of large cargoes across the nuclear envelope. Cargo is recruited, …