Naegleria fowleri is a single-cell organism living in warm freshwater that can become a deadly
human pathogen known as a brain-eating amoeba. The condition caused by N. fowleri, …

Copper is a trace metal that is necessary for all organisms but toxic when present in excess.
Different mechanisms to avoid copper toxicity have been reported to date in pathogenic …

Copper plays a fundamental role in aerobic metabolism, but its role is double-edged, given
its toxicity. Our understanding of copper metabolism in parasites remains rudimentary, …

Although copper is an essential nutrient crucial for many biological processes, an excessive
concentration can be toxic and lead to cell death. The metabolism of this two-faced metal …

Acanthamoeba castellanii is a ubiquitously distributed amoeba that can be found in soil, dust,
natural and tap water, air conditioners, hospitals, contact lenses and other environments. It …

… The precipitate was suspended in a buffer containing 0.1 M Tris HCl (pH 8.0), 0.1 M EDTA,
and 1% PVP, followed by fractional ultrasonication with three low power pulses. SDS was …

背景 当前这项研究的目的是在糖尿病患者中调查乙醛变性对抗氧化物酶活性的影响. 方法 在乙
醛变性之前以及之后在体外分别测定市售的抗氧化物酶(过氧化氢酶,谷胱甘肽过氧化物酶[GPx]…

We have suggested that the molecular mechanism of vascular wall damage in diabetes is
not substantially different from that in atherosclerosis. Thus, it can be assumed that aldehyde-…

… I declare that the involvement of Maria Grechnikova in this work was substantial and that …
coli, M. tuberculosis, and Salmonella typhimurium mutants lacking Cu+-exporting ATPases …

Methylglyoxal at a concentration of 5 mM caused a significant inhibition of superoxide anion
radical (O 2 ·- ) comparable to the effect of Tirone. In the process of O 2 ·- generation in the …