… Takaku and M. Suzuki for their contribution to GSC development. We also thank Y. Ruan
for fruitful discussions and our collaboration within the FANTOM 3 project, and M. Dushay for …

This study describes comprehensive polling of transcription start and termination sites and
analysis of previously unidentified full-length complementary DNAs derived from the mouse …

Mammalian promoters can be separated into two classes, conserved TATA box–enriched
promoters, which initiate at a well-defined site, and more plastic, broad and evolvable CpG-…

… However, the reaction vial has a membrane at the bottom (indicated by “M” in the figure),
and by centrifugation the reaction mix can be pressed through the membrane to remove small …

Background Adults with a low socioeconomic position (SEP) are more likely to engage in
unhealthy diets as compared to adults with high SEP. However, individual-level educational …

We introduce cap analysis gene expression (CAGE), which is based on preparation and
sequencing of concatamers of DNA tags deriving from the initial 20 nucleotides from 5′ end …

… To 50 μg of total RNA, add NaCl to a final concentration of 0.25 M and combine with an
equal volume of isopropanol. Precipitate the RNA at −20 C for 30 min and centrifuge at 15,000g …

Background DNA methylation in promoters is closely linked to downstream gene repression.
However, whether DNA methylation is a cause or a consequence of gene repression …

Background miR-122 is an important host factor for hepatitis C virus (HCV) replication. The
aim of this study was to assess the safety and tolerability, pharmacokinetics, and antiviral …

Naturally occurring regulatory T (Treg) cells, which specifically express the transcription
factor forkhead box P3 (Foxp3), are engaged in the maintenance of immunological self-…