User profiles for M. Hoelzer

Martin Hölzer

Robert Koch Institute, MF1 (Bioinformatics)
Verified email at rki.de
Cited by 1796

Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research

…, D Heider, M Hoffmann, M Hölzer… - Briefings in …, 2021 - academic.oup.com
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the
family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of …

De novo transcriptome assembly: A comprehensive cross-species comparison of short-read RNA-Seq assemblers

M Hölzer, M Marz - Gigascience, 2019 - academic.oup.com
… Yes graphic graphic 7 m 8 h 49 m 2 h 44 m 0.6 29.1 9.6 [12] … Yes graphic graphic 7 m 8 h
49 m 2 h 44 m 0.6 29.1 9.6 [12] … Yes c graphic graphic 11 m 7 h 24 m 2 h 17 m 5.0 44.2 19.5 […

DNA repair and the evolution of transformation in the bacterium Bacillus subtilis.

RE Michod, MF Wojciechowski, MA Hoelzer - Genetics, 1988 - academic.oup.com
The purpose of the work reported here is to test the hypothesis that natural genetic transformation
in the bacterium Bacillus subtilis has evolved as a DNA repair system. Specifically, …

Advancing precision vaccinology by molecular and genomic surveillance of severe acute respiratory syndrome coronavirus 2 in Germany, 2021

DY Oh, M Hölzer, S Paraskevopoulou… - Clinical infectious …, 2022 - academic.oup.com
Background Comprehensive pathogen genomic surveillance represents a powerful tool to
complement and advance precision vaccinology. The emergence of the Alpha variant in …

Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions

…, DM Proctor, C Deming, P Saary, M Hölzer… - Nature …, 2022 - nature.com
Human skin functions as a physical barrier to foreign pathogen invasion and houses numerous
commensals. Shifts in the human skin microbiome have been associated with conditions …

Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis

…, R Madhugiri, J Ziebuhr, M Hölzer, M Marz - Genome …, 2019 - genome.cshlp.org
Sequence analyses of RNA virus genomes remain challenging owing to the exceptional
genetic plasticity of these viruses. Because of high mutation and recombination rates, genome …

Purification and Partial Characterization of Tryptophan 7‐Halogenase (PrnA) from Pseudomonas fluorescens

S Keller, T Wage, K Hohaus, M Hölzer… - Angewandte Chemie …, 2000 - Wiley Online Library
… Elution was achieved with a linear NaCl gradient (0 ± 0.5m). Fractions that contained
PrnA, which was detected by sodium dodecylsulfate/polyacrylamide gel electrophoresis (SDS-…

Evidence for the existence of a new genus Chlamydiifrater gen. nov. inside the family Chlamydiaceae with two new species isolated from flamingo (Phoenicopterus …

F Vorimore, M Hölzer, EM Liebler-Tenorio… - Systematic and Applied …, 2021 - Elsevier
The family Chlamydiaceae currently comprises a single genus Chlamydia, with 11 validly
published species and seven more taxa. It includes the human pathogens Chlamydia (C.) …

Clinical findings and legal resolution in sexual assault

JE Tintinalli, M Hoelzer - Annals of Emergency Medicine, 1985 - Elsevier
… [Tintinal]i JE, Hoelzer H: Clinical findings and legal resolution in sexual assault. Ann Emerg
Med May … SEXUAL ASSAULT Tintinalli & Hoelzer … SEXUAL ASSAULT Tintinalli & Hoelzer

[HTML][HTML] Comparative Genome Analysis of 33 Chlamydia Strains Reveals Characteristic Features of Chlamydia Psittaci and Closely Related Species

M Hölzer, LM Barf, K Lamkiewicz, F Vorimore… - Pathogens, 2020 - mdpi.com
… pipeline freely available at github.com/hoelzer-lab/ribap and implemented using the workflow
… following command: nextflow run hoelzer-lab/ribap -r v0.4 --fasta ‘*.fasta’ --tree --tmlim 240. …