User profiles for M. Isabel Loza
Maria Isabel Loza RiveraThe Morton Arboretum Verified email at mortonarb.org Cited by 523 |
[PDF][PDF] Identification of new activators of mitochondrial fusion reveals a link between mitochondrial morphology and pyrimidine metabolism
…, M Palacin, PM Fernández-Salguero, MI Loza… - Cell chemical …, 2018 - cell.com
Mitochondria are dynamic organelles that produce most of the cellular ATP, and are involved
in many other cellular functions such as Ca 2+ signaling, differentiation, apoptosis, cell …
in many other cellular functions such as Ca 2+ signaling, differentiation, apoptosis, cell …
[HTML][HTML] Elevational gradients in β-diversity reflect variation in the strength of local community assembly mechanisms across spatial scales
…, L Cayola, G Arellano, MI Loza, V Torrez, M Cornejo… - PLoS …, 2015 - journals.plos.org
Despite long-standing interest in elevational-diversity gradients, little is known about the
processes that cause changes in the compositional variation of communities (β-diversity) across …
processes that cause changes in the compositional variation of communities (β-diversity) across …
[HTML][HTML] Pharmacological inhibition of soluble epoxide hydrolase as a new therapy for Alzheimer's disease
…, R Corpas, C Sanfeliu, B Pérez, MI Loza… - …, 2020 - Springer
The inhibition of the enzyme soluble epoxide hydrolase (sEH) has demonstrated clinical
therapeutic effects in several peripheral inflammatory-related diseases, with 3 compounds in …
therapeutic effects in several peripheral inflammatory-related diseases, with 3 compounds in …
The role of niche overlap, environmental heterogeneity, landscape roughness and productivity in shaping species abundance distributions along the Amazon–Andes …
Aim Statistical and ecological mechanisms shape species abundance distributions (SADs).
A lack of correlation between ecological gradients and SAD shape would suggest that SADs …
A lack of correlation between ecological gradients and SAD shape would suggest that SADs …
[HTML][HTML] FunAndes–A functional trait database of Andean plants
…, M Bauters, C Ben Saadi, C Blundo, M Cabrera… - Scientific data, 2022 - nature.com
We introduce the FunAndes database, a compilation of functional trait data for the Andean
flora spanning six countries. FunAndes contains data on 24 traits across 2,694 taxa, for a total …
flora spanning six countries. FunAndes contains data on 24 traits across 2,694 taxa, for a total …
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
…, S Osuna, C Morisseau, MI Loza… - Journal of medicinal …, 2021 - ACS Publications
The pharmacological inhibition of soluble epoxide hydrolase (sEH) is efficient for the
treatment of inflammatory and pain-related diseases. Numerous potent sEH inhibitors (sEHIs) …
treatment of inflammatory and pain-related diseases. Numerous potent sEH inhibitors (sEHIs) …
Clinical validation of blood/brain glutamate grabbing in acute ischemic stroke
Objective Blood/brain‐glutamate grabbing is an emerging concept in the treatment of acute
ischemic stroke, where essentially the deleterious effects of glutamate after ischemia are …
ischemic stroke, where essentially the deleterious effects of glutamate after ischemia are …
[HTML][HTML] Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease
…, MB Phillips, DS Patel, C Griñán-Ferré, MI Loza… - European journal of …, 2022 - Elsevier
Currently, of the few accessible symptomatic therapies for Alzheimer's disease (AD), memantine
is the only N-methyl-d-aspartate receptor (NMDAR) blocker approved by the FDA. This …
is the only N-methyl-d-aspartate receptor (NMDAR) blocker approved by the FDA. This …
Synthesis and Biological Activity of New Potential Agonists for the Human Adenosine A2A Receptor
…, G Rosell, JL Díaz, J Brea, MI Loza… - Journal of medicinal …, 2004 - ACS Publications
New adenosine derivatives have been synthesized and tested as putative agonists of adenosine
receptors. Compounds 2−6 derive from the introduction of several types of substituents (…
receptors. Compounds 2−6 derive from the introduction of several types of substituents (…
New Serotonin 5-HT2A, 5-HT2B, and 5-HT2C Receptor Antagonists: Synthesis, Pharmacology, 3D-QSAR, and Molecular Modeling of (Aminoalkyl)benzo and …
…, E Raviña, NB Centeno, A Carotti, MI Loza - Journal of Medicinal …, 2002 - ACS Publications
A series of 52 conformationally constrained butyrophenones have been synthesized and
pharmacologically tested as antagonists at 5-HT 2A , 5-HT 2B , and 5-HT 2C serotonin …
pharmacologically tested as antagonists at 5-HT 2A , 5-HT 2B , and 5-HT 2C serotonin …