… Brain slices (30μ m) were dually labeled with antibodies against the MR (green) and GR (red).
Each cluster is about 10 receptor molecules. Yellow indicates colocalized MR and GR …

Corticosteroid hormones secreted by the adrenal cortex protect the brain against adverse
events and are essential for cognitive performance. However, in recent literature, the central …

In response to stress, the brain activates several neuropeptide-secreting systems. This eventually
leads to the release of adrenal corticosteroid hormones, which subsequently feed back …

Studies of psychiatric disorders have traditionally focused on emotional symptoms such as
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …

The effects of stress on learning and memory are not always clear: both facilitating and
impairing influences are described in the literature. Here we propose a unifying theory, which …

The impact of stress on brain function is increasingly recognized. Various substances are
released in response to stress and can influence distinct neuronal circuits, but the functional …

Stress initiates an intricate response that affects diverse cognitive and affective domains, with
the goal of improving survival chances in the light of changing environmental challenges. …

It is well known that stressful experiences may affect learning and memory processes. Less
clear is the exact nature of these stress effects on memory: both enhancing and impairing …

The adrenal hormone corticosterone transcriptionally regulates responsive genes in the
rodent hippocampus through nuclear mineralocorticoid and glucocorticoid receptors. Via this …

… Based on these findings, the high dosage (100 nm) used in the current study mimicked
physiological, stress-induced CORT levels. Perhaps most importantly, the 100 nm concentration …