It has been long-established that cancer and thrombosis are linked, but the exact underlying
pathological mechanism remains to be unraveled. As the initiator of the coagulation cascade…

OBJECTIVE: To review the anatomy and physiology of the vagina, the merits of vaginal drug
administration, and the currently available vaginal drug-administration systems. DESIGN: …

Metastasis results from a complex set of traits acquired by tumor cells, distinct from those
necessary for tumorigenesis. Here, we investigate the contribution of enhancer elements to the …

… × 2 Gy) with concomitant temozolomide chemotherapy (75 mg/m 2 once daily), followed by
six cycles of temozolomide monotherapy (150 mg/m 2 once daily for 5 days per 28‐day cycle)…

Business codes are a widely used management instrument. Research into the effectiveness
of business codes has, however, produced conflicting results. The main reasons for the …

… To define these virtues, Kaptein conducted a qualitative analysis of 150 actual cases that
included a variety of types of unethical employee conduct that was (partly) caused by the …

Business codes are an oft-cited management instrument. But how common are codes among
multinationals? And what is their content? In an unprecedented study, the codes of the …

… Dr Muel Kaptein and Dr Johan Wempe have been active as consultants in the field of … Muel
Kaptein and Johan Wempe are respectively senior manager and partner at KPMG Ethics & …

… The quality of ethical culture is negatively related to the frequency of wrongdoing (Kaptein,
2010), but as this study shows, a healthy ethical culture generally results in a greater …

… The items for ethical culture and unethical behavior were identical to the items of the survey
Kaptein (2008a, 2008b) developed in Dutch. Following the suggestions of Harkness and …