The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) …

Sickle cell disease and β-thalassaemia are inherited haemoglobinopathies resulting in
structural and quantitative changes in the β-globin chain. These changes lead to instability of the …

The β-thalassemias are a group of hereditary hematological diseases caused by over 300
mutations of the adult β-globin gene. Together with sickle cell anemia, thalassemia …

Inherited haemoglobinopathies are the most common monogenic diseases, with millions of
carriers and patients worldwide. At present, we know several hundred disease-causing …

Sickle Cell Disease ( SCD ) is an increasing global health problem and presents significant
challenges to European health care systems. Newborn screening ( NBS ) for SCD enables …

To discern whether an association exists between specific combinations of polymorphisms
of the prion protein (PrP) and natural scrapie in Cyprus goats, 250 goats were examined, …

Rare diseases pose a global challenge, in that their collective impact on health systems is
considerable, whereas their individually rare occurrence impedes research and development …

Haemoglobinopathies are the most common monogenic diseases, posing a major public
health challenge worldwide. Cyprus has one the highest prevalences of thalassaemia in the …

A comparative assessment of excess storage iron distribution in the liver, heart, spleen and
pancreas of β-thalassemia major (β-ΤΜ) patients has been carried out using magnetic …

… Briefly, 40 PCR libraries were pooled together to get a stock of 10 nM. One microliter of the
10 nM stock was denaturated with NaOH, diluted to 6.5 pM and hybridised onto the flowcell. …