Objective: A fine-tuned balance of glucocorticoid receptor (GR) activation is essential for organ
formation, with disturbances influencing many health outcomes. In utero, glucocorticoids …

… 5 libraries were pooled per lane for a total coverage of on average 50 M reads/library. Raw
reads were processed using FastQC 53 and cutadapt 54 and aligned using the STAR aligner …

Ageing is a complex biological process with changes in the brain at the structural and
functional level, especially in the prefrontal cortex. Age represents the biggest risk factor for …

Disruptions in the tightly regulated process of human brain development have been linked
to increased risk for brain and mental illnesses. While the genetic contribution to these …

… Correspondence to Uwe Koedel, Clinics of the Ludwig-Maximilians-University, Department of
Neurology, Marchioninistr. 15, D-81377 Munich, Germany Fax: +49 89 7095 5561; e-mail: [email …

Objectives The utility of cerebrospinal fluid (CSF) CXCL13 for diagnosis of acute Lyme
neuroborreliosis (LNB) has been debated and the test is not yet routinely performed. This study's …

Despite antibiotic therapy and supportive intensive care, the morbidity and mortality of
pneumococcal meningitis remain unacceptably high. During the last years, reactive oxygen (ROS) …

Spurred by the federal Race to the Top competition, the state of Tennessee implemented a
comprehensive statewide educator evaluation system in 2011. The new system is designed …

Introduction Intracranial vascular complications are an important complication of acute bacterial
meningitis. Ischemic stroke in meningitis is reported as a result of vasculitis, vasospasm, …

Background. Recent studies have suggested that, in addition to Toll-like receptor (TLR) 2,
other pattern recognition receptors mediate activation of the immune response after infection …