User profiles for M. Kotini

Maria Kotini

Biozentrum Basel
Verified email at unibas.ch
Cited by 505

[HTML][HTML] Connexins in migration during development and cancer

M Kotini, R Mayor - Developmental biology, 2015 - Elsevier
Connexins, the gap junction proteins, through their multitude of actions are implicated in a
variety of cell processes during animal development and cancer. They allow direct or …

[HTML][HTML] Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo

M Kotini, EH Barriga, J Leslie, M Gentzel… - Nature …, 2018 - nature.com
… Subsequently of acid elution with 0.1 M glycine pH 2.5, the pH of the eluates was adjusted
to pH 8.0 with 0.5 M Tris. For protein digestion samples were incubated overnight with 2 µg …

Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo

AL Law, A Vehlow, M Kotini, L Dodgson… - Journal of Cell …, 2013 - rupress.org
M. Kotini is supported by a PhD scholarship from the Latsis Public Benefit Foundation. E. …
Kotini and E. Theveneau performed all the Xenopus experiments; R. Mayor designed and …

[HTML][HTML] Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

…, P Casado, SD Castillo, P Kobialka, MP Kotini… - Nature …, 2018 - nature.com
Angiogenesis is a dynamic process relying on endothelial cell rearrangements within vascular
tubes, yet the underlying mechanisms and functional relevance are poorly understood. …

[PDF][PDF] Vinculin controls endothelial cell junction dynamics during vascular lumen formation

MP Kotini, MM van der Stoel, J Yin, MK Han… - Cell reports, 2022 - cell.com
Blood vessel morphogenesis is driven by coordinated endothelial cell behaviors. Active
remodeling of cell-cell junctions promotes cellular plasticity while preserving vascular integrity. …

Sprouting and anastomosis in the Drosophila trachea and the vertebrate vasculature: Similarities and differences in cell behaviour

MP Kotini, MA Mäe, HG Belting, C Betsholtz… - Vascular …, 2019 - Elsevier
Branching morphogenesis is a fascinating process whereby a simple network of biological
tubes increases its complexity by adding new branches to existing ones, generating an …

Interferon-γ drives macrophage reprogramming, cerebrovascular remodelling, and cognitive dysfunction in a zebrafish and a mouse model of ion imbalance and …

…, M Perrotta, R Carnevale, MP Kotini… - Cardiovascular …, 2023 - academic.oup.com
… Reduced integrity of endothelial junction, visualized by platelet endothelial cell adhesion
molecule (PECAM)-EGFP expression (M), is expressed as percentages of junctional coverage …

[HTML][HTML] Vinculin strengthens the endothelial barrier during vascular development

…, MP Kotini, RM Schoon, M Affolter… - Vascular …, 2023 - vb.bioscientifica.com
Remodelling of cell–cell junctions is crucial for proper tissue development and barrier
function. The cadherin-based adherens junctions anchor via β-catenin and α-catenin to the …

[HTML][HTML] The Leishmania donovani histidine acid ecto-phosphatase LdMAcP: insight into its structure and function

A Papadaki, AS Politou, D Smirlis, MP Kotini… - Biochemical …, 2015 - ncbi.nlm.nih.gov
Acid ecto-phosphatase activity has been implicated in Leishmania donovani promastigote
virulence. In the present study, we report data contributing to the molecular/structural and …

[HTML][HTML] Probing the effects of the FGFR-inhibitor derazantinib on vascular development in Zebrafish embryos

MP Kotini, F Bachmann, J Spickermann… - Pharmaceuticals, 2020 - mdpi.com
Angiogenesis is a fundamental developmental process and a hallmark of cancer progression.
Receptor tyrosine kinases (RTK) are targets for cancer therapy which may include their …