Neurogenesis is widespread in the zebrafish adult brain through the maintenance of active
germinal niches. To characterize which progenitor properties correlate with this extensive …

Maintaining the homeostasis of germinal zones in adult organs is a fundamental but
mechanistically poorly understood process. In particular, what controls stem cell activation remains …

Live imaging of adult neural stem cells (aNSCs) in vivo is a technical challenge in the
vertebrate brain. Here, we achieve long-term imaging of the adult zebrafish telencephalic …

Haematopoietic stem cells are generated from the haemogenic endothelium (HE) located in
the floor of the dorsal aorta (DA). Despite being integral to arteries, it is controversial …

Neural stem cell (NSC) populations persist in the adult vertebrate brain over a lifetime, and
their homeostasis is controlled at the population level through unknown mechanisms. Here, …

Gata2 is a key transcription factor required to generate Haematopoietic Stem and Progenitor
Cells (HSPCs) from haemogenic endothelium (HE); misexpression of Gata2 leads to …

Alcohol consumption interferes with gastrointestinal transit causing symptoms in alcoholic
patients. Nitric oxide (NO), synthesized by neuronal nitric oxide synthase (nNOS) plays an …

Enhancers can regulate the transcription of genes over long genomic distances. This is
thought to lead to selection against genomic rearrangements within such regions that may …

In situ hybridization (ISH) is an important technique that enables researchers to study mRNA
distribution in situ and has been a critical technique in developmental biology for decades. …

Advances in genome engineering have resulted in the generation of numerous zebrafish
mutant lines. A commonly used method to assess gene expression in the mutants is in situ …