Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. …

The human reference genome assembly plays a central role in nearly all aspects of today's
basic and clinical research. GRCh38 is the first coordinate-changing assembly update since …

After two decades of improvements, the current human reference genome (GRCh38) is the
most accurate and complete vertebrate genome ever produced. However, no single …

The availability of a high quality human genome assembly has revolutionized biomedical
research. Genomics has now entered the realm of clinical genetics, with many groups using …

The complete assembly of each human chromosome is essential for understanding human
biology and evolution 1 , 2 . Here we use complementary long-read sequencing …

The importance of the Gallus gallus (chicken) as a model organism and agricultural animal
merits a continuation of sequence assembly improvement efforts. We present a new version …

INTRODUCTION The rhesus macaque (Macaca mulatta) is one of the most widely used
nonhuman primate (NHP) models for studying human biology and disease. As a representative …

We describe a genome reference of the African green monkey or vervet (Chlorocebus
aethiops). This member of the Old World monkey (OWM) superfamily is uniquely valuable for …

The domestic cat (Felis catus) numbers over 94 million in the USA alone, occupies households
as a companion animal, and, like humans, suffers from cancer and common and rare …

Identifying the genetic factors that underlie complex traits is central to understanding the
mechanistic underpinnings of evolution. Cave-dwelling Astyanax mexicanus populations are …