We show that the nuclear architecture of rod photoreceptor cells differs fundamentally in
nocturnal and diurnal mammals. The rods of diurnal retinas possess the conventional …

Phase separation of mixtures of oppositely charged polymers provides a simple and direct
route to compartmentalisation via complex coacervation, which may have been important for …

Knowledge of the interplay between the morphology, composition and optical appearance
of biological photonic systems can provide broad inspiration for novel artificial photonic …

Liquid–liquid phase separation (LLPS) of proteins containing intrinsically disordered
regions (IDRs) has been proposed as a mechanism underlying the formation of membrane-less …

… M. Kreysing reports employment with Uniklinik Heidelberg. C. Morath reports employment
with Nierenzentrum Heidelberg and TolerogenixX GmbH; having ownership interest in …

… With an average embryo volume V embryo of about 30 ⋅ 1 0 3 μ m 3 we find a relative
volume of the condensed P granule phase of about 0.1% [Fig. 2D and SI Appendix, Fig. S2; …

The replication of nucleic acids is central to the origin of life. On the early Earth, suitable non-equilibrium
boundary conditions would have been required to surmount the effects of …

Cells sense elevated temperatures and mount an adaptive heat shock response that involves
changes in gene expression, but the underlying mechanisms, particularly on the level of …

Micro-scale optical components play a crucial role in imaging and display technology,
biosensing, beam shaping, optical switching, wavefront-analysis, and device miniaturization. …

Recent advances in cell biology enable precise molecular perturbations. The spatiotemporal
organization of cells and organisms, however, also depends on physical processes such …