[HTML][HTML] Antiretroviral prophylaxis for HIV prevention in heterosexual men and women

…, KK Thomas, L Kidoguchi, M Krows… - New England journal …, 2012 - Mass Medical Soc
Background Antiretroviral preexposure prophylaxis is a promising approach for preventing
human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations. Methods …

[HTML][HTML] Adherence to antiretroviral prophylaxis for HIV prevention: a substudy cohort within a clinical trial of serodiscordant couples in East Africa

…, NC Ware, KK Thomas, D Donnell, M Krows… - PLoS …, 2013 - journals.plos.org
Background Randomized clinical trials of oral antiretroviral pre-exposure prophylaxis (PrEP)
for HIV prevention have widely divergent efficacy estimates, ranging from 0% to 75%. These …

Acute hepatitis C in a contemporary US cohort: modes of acquisition and factors influencing viral clearance

CC Wang, E Krantz, J Klarquist, M Krows… - The Journal of …, 2007 - academic.oup.com
Background. Acute hepatitis C virus (HCV) infection is often asymptomatic; thus, its epidemiology
and natural history are difficult to define. Methods. Acute HCV infection was identified …

Hydroxychloroquine as postexposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 infection: a randomized trial

…, R Hoffman, TT Schaafsma, ML Krows… - Annals of internal …, 2021 - acpjournals.org
Background: Effective prevention against coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently limited to …

High HIV testing uptake and linkage to care in a novel program of home-based HIV counseling and testing with facilitated referral in KwaZulu-Natal, South Africa

…, Z Phakathi, P Joseph, M Krows… - JAIDS Journal of …, 2013 - journals.lww.com
Objective: For antiretroviral therapy (ART) to have a population-level HIV prevention impact,
high levels of HIV testing and effective linkages to HIV care among HIV-infected persons are …

[HTML][HTML] Community-based antiretroviral therapy versus standard clinic-based services for HIV in South Africa and Uganda (DO ART): a randomised trial

…, D Pillay, NC Ware, TT Schaafsma, ML Krows… - The lancet Global …, 2020 - thelancet.com
Background Community-based delivery of antiretroviral therapy (ART) for HIV, including ART
initiation, clinical and laboratory monitoring, and refills, could reduce barriers to treatment …

Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: a …

…, H Humphries, B Turyamureeba, P Joseph, M Krows… - The lancet HIV, 2014 - thelancet.com
Background Antiretroviral therapy significantly decreases HIV-associated morbidity, mortality,
and HIV transmission through HIV viral load suppression. In settings of high prevalence, …

Comparison of racial, ethnic, and geographic location diversity of participants enrolled in clinic-based vs 2 remote COVID-19 clinical trials

J Stewart, ML Krows, TT Schaafsma… - JAMA Network …, 2022 - jamanetwork.com
Importance Racial and ethnic diversity among study participants is associated with improved
generalizability of clinical trial results and may address inequities in evidence that informs …

Uptake of antiretroviral therapy and male circumcision after community-based HIV testing and strategies for linkage to care versus standard clinic referral: a multisite …

…, B Turyamureeba, P Joseph, M Krows… - The lancet HIV, 2016 - thelancet.com
Background Male circumcision decreases HIV acquisition by 60%, and antiretroviral
therapy (ART) almost eliminates HIV transmission from HIV-positive people who are virally …

[HTML][HTML] Characteristics of HIV-1 serodiscordant couples enrolled in a clinical trial of antiretroviral pre-exposure prophylaxis for HIV-1 prevention

…, G John-Stewart, L Kidoguchi, D Panteleeff, M Krows… - PloS one, 2011 - journals.plos.org
Introduction Stable heterosexual HIV-1 serodiscordant couples in Africa have high HIV-1
transmission rates and are a critical population for evaluation of new HIV-1 prevention …