G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm
…, M Bossolasco, M Leduc, M Grandbois… - Canadian journal of …, 2006 - cdnsciencepub.com
G-protein-coupled receptors (GPCRs) comprise a wide family of monomeric heptahelical
glycoproteins that recognize a broad array of extracellular mediators including cationic amines, …
glycoproteins that recognize a broad array of extracellular mediators including cationic amines, …
Cold and trapped metastable noble gases
W Vassen, C Cohen-Tannoudji, M Leduc, D Boiron… - Reviews of Modern …, 2012 - APS
… In this case also m ž 0 and m ž Ā1 atoms as well as mixtures of different m states can be
trapped. As only a spin-polarized gas of either m ž þ1 or m ž Ā1 atoms is stable against Penning …
trapped. As only a spin-polarized gas of either m ž þ1 or m ž Ā1 atoms is stable against Penning …
[HTML][HTML] Clinical whole-exome sequencing for the diagnosis of mendelian disorders
…, R Person, MR Bekheirnia, MS Leduc… - … England Journal of …, 2013 - Mass Medical Soc
Background Whole-exome sequencing is a diagnostic approach for the identification of
molecular defects in patients with suspected genetic disorders. Methods We developed technical…
molecular defects in patients with suspected genetic disorders. Methods We developed technical…
Molecular findings among patients referred for clinical whole-exome sequencing
…, N Veeraraghavan, A Hawes, T Chiang, M Leduc… - Jama, 2014 - jamanetwork.com
Importance Clinical whole-exome sequencing is increasingly used for diagnostic evaluation
of patients with suspected genetic disorders. Objective To perform clinical whole-exome …
of patients with suspected genetic disorders. Objective To perform clinical whole-exome …
[HTML][HTML] An overview of duplicated gene detection methods: Why the duplication mechanism has to be accounted for in their choice
T Lallemand, M Leduc, C Landès, C Rizzon, E Lerat - Genes, 2020 - mdpi.com
Gene duplication is an important evolutionary mechanism allowing to provide new genetic
material and thus opportunities to acquire new gene functions for an organism, with major …
material and thus opportunities to acquire new gene functions for an organism, with major …
Self-condensing vinyl polymerization: an approach to dendritic materials
JMJ Frechet, M Henmi, I Gitsov, S Aoshima, MR Leduc… - Science, 1995 - science.org
Self-condensing vinyl polymerization was used to produce dendritic polymers with both
highly branched structures and numerous reactive groups. A vinyl monomer will undergo self-…
highly branched structures and numerous reactive groups. A vinyl monomer will undergo self-…
Bose-Einstein condensation of metastable helium
…, F Perales, E Rasel, CS Unnikrishnan, M Leduc… - Physical Review Letters, 2001 - APS
We have observed a Bose-Einstein condensate in a dilute gas of 4 He in the 2 S 1 3 metastable
state. We find a critical temperature of (4.7±0.5) μ K and a typical number of atoms at the …
state. We find a critical temperature of (4.7±0.5) μ K and a typical number of atoms at the …
Use of exome sequencing for infants in intensive care units: ascertainment of severe single-gene disorders and effect on medical management
Importance While congenital malformations and genetic diseases are a leading cause of
early infant death, to our knowledge, the contribution of single-gene disorders in this group is …
early infant death, to our knowledge, the contribution of single-gene disorders in this group is …
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
…, DR Varma, S Tremblay, M Leduc… - Nature medicine, 2008 - nature.com
… We calculated the ratios of the areas of the peaks at m/z 297 and m/z 301 and converted
them to weight of endogenous succinate per cell protein content or total sample weight. Details …
them to weight of endogenous succinate per cell protein content or total sample weight. Details …
[HTML][HTML] Potential role of microglia in retinal blood vessel formation
…, F Sennlaub, E Levavasseur, M Leduc… - … & visual science, 2006 - arvojournals.org
purpose. The role of microglia, present in the retina early in development before vascularization,
remains ill defined. The authors investigated whether microglia are implicated in retinal …
remains ill defined. The authors investigated whether microglia are implicated in retinal …