Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

…, EM Cox, CR Houchens, ML Grayson… - The Lancet infectious …, 2018 - thelancet.com
Background The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity
and mortality worldwide. Due to its large public health and societal implications, multidrug-…

Reduced Vancomycin Susceptibility in Staphylococcus aureus, Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains …

…, PDR Johnson, TP Stinear, ML Grayson - Clinical microbiology …, 2010 - Am Soc Microbiol
The emergence of vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous
vancomycin-intermediate Staphylococcus aureus (hVISA) over the past decade has …

SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia

…, ML Grayson - Clinical infectious …, 2008 - academic.oup.com
Background . Existing severity assessment tools, such as the pneumonia severity index (PSI)
and CURB-65 (tool based on confusion, urea level, respiratory rate, blood pressure, and …

Probing to bone in infected pedal ulcers: a clinical sign of underlying osteomyelitis in diabetic patients

ML Grayson, GW Gibbons, K Balogh, E Levin… - Jama, 1995 - jamanetwork.com
Objective. —To assess a bedside technique for diagnosing osteomyelitis. Design. —We
prospectively assessed infected pedal ulcers for detectable bone by probing with a sterile, blunt, …

Treatment Outcomes for Serious Infections Caused by Methicillin-Resistant Staphylococcus aureus with Reduced Vancomycin Susceptibility

…, AJ Morris, BC Mayall, ML Grayson - Clinical Infectious …, 2004 - academic.oup.com
Although infections caused by methicillin-resistant Staphylococcus aureus with reduced
vancomycin susceptibility (SA-RVS) have been reported from a number of countries, including …

Clinical Features Associated with Bacteremia Due to Heterogeneous Vancomycin-Intermediate Staphylococcus aureus

…, PDR Johnson, BP Howden, ML Grayson - Clinical infectious …, 2004 - academic.oup.com
We assessed all episodes of methicillin-resistant Staphylococcus aureus (MRSA)
bacteremia at our hospital during a 12-month period (n = 53) and compared those due to …

[HTML][HTML] Core components for effective infection prevention and control programmes: new WHO evidence-based recommendations

…, J Reilly, L Price, M Egger, ML Grayson… - … Resistance & Infection …, 2017 - Springer
Health care-associated infections (HAI) are a major public health problem with a significant
impact on morbidity, mortality and quality of life. They represent also an important economic …

Efficacy of an alcohol/chlorhexidine hand hygiene program in a hospital with high rates of nosocomial methicillin‐resistant Staphylococcus aureus (MRSA) infection

…, C Bolger, H Naidoo, ML Grayson - Medical Journal of …, 2005 - Wiley Online Library
Objective: To assess the effect of a multifaceted hand hygiene culture‐change program on
health care worker behaviour, and to reduce the burden of nosocomial methicillin‐resistant …

Efficacy of soap and water and alcohol-based hand-rub preparations against live H1N1 influenza virus on the hands of human volunteers

ML Grayson, S Melvani, J Druce, IG Barr… - Clinical Infectious …, 2009 - academic.oup.com
Background . Although pandemic and avian influenza are known to be transmitted via
human hands, there are minimal data regarding the effectiveness of routine hand hygiene (HH) …

A quantitative assessment of the efficacy of surgical and N95 masks to filter influenza virus in patients with acute influenza infection

…, JD Druce, C Birch, ML Grayson - Clinical Infectious …, 2009 - academic.oup.com
We assessed the in vivo efficacy of surgical and N95 (respirator) masks to filter reverse
transcription-polymerase chain reaction (RT-PCR)-detectable virus when worn correctly by …