User profiles for M. Luftig

Micah Luftig

Duke University
Verified email at duke.edu
Cited by 15961

[HTML][HTML] The viral and cellular microRNA targetome in lymphoblastoid cell lines

…, R Feederle, HJ Delecluse, MA Luftig… - PLoS …, 2012 - journals.plos.org
… The authors also thank the members of the Cullen and Ohler labs for helpful discussions,
the Luftig lab members for producing the EF3D and LCL35 LCLs, the Duke Flow Core for …

[HTML][HTML] To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis

AM Price, MA Luftig - PLoS pathogens, 2015 - journals.plos.org
Epstein-Barr virus (EBV), a γ-herpesvirus, was the first human tumor virus discovered fifty
years ago in endemic Burkitt lymphoma [1]. Surprisingly, EBV was subsequently recognized to …

Viruses and the DNA damage response: activation and antagonism

MA Luftig - Annual review of virology, 2014 - annualreviews.org
… The human immunodeficiency virus (HIV) Vpr protein also induces a robust ATR-mediated
DDR due to perturbation of the G 2 -M checkpoint through interactions with the DDB1 protein (…

Proteins of purified Epstein-Barr virus

E Johannsen, M Luftig, MR Chase… - Proceedings of the …, 2004 - National Acad Sciences
Mature Epstein-Barr virus (EBV) was purified from the culture medium of infected lymphocytes
made functionally conditional for Zta activation of lytic replication by an in-frame fusion …

Genetic heterogeneity of diffuse large B-cell lymphoma

…, AJ Johnson, JC Byrd, MA Luftig… - Proceedings of the …, 2013 - National Acad Sciences
Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma in adults. The
disease exhibits a striking heterogeneity in gene expression profiles and clinical outcomes, …

Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs

…, AM Evens, LI Gordon, M Luftig… - Blood, The Journal …, 2010 - ashpublications.org
A role for microRNA (miRNA) has been recognized in nearly every biologic system examined
thus far. A complete delineation of their role must be preceded by the identification of all …

[PDF][PDF] An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells

…, W Kim, K Hu, J Guo, D Tainter, E Rusyn, MA Luftig - Cell host & …, 2010 - cell.com
Epstein-Barr virus (EBV), an oncogenic herpesvirus that causes human malignancies,
infects and immortalizes primary human B cells in vitro into indefinitely proliferating …

Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus

…, E Gottwein, RL Skalsky, MA Luftig… - Journal of …, 2010 - Am Soc Microbiol
Infection of resting primary human B cells by Epstein-Barr virus (EBV) results in their
transformation into indefinitely proliferating lymphoblastoid cell lines (LCLs). LCL formation serves …

Epstein–Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKKα-dependent noncanonical NF-κB activation

M Luftig, T Yasui, V Soni, MS Kang… - Proceedings of the …, 2004 - National Acad Sciences
… IKKα, IKKβ, and IKKγ KO murine embryonic fibroblasts (MEFs) were kindly provided by M. …
/PAGE and immunoblot with IKKγ (kindly provided by M. Horwitz; ref. 64) and tubulin control …

[HTML][HTML] Structure of herpes simplex virus glycoprotein D bound to the human receptor nectin-1

…, EC Settembre, AK Bhargava, MA Luftig… - PLoS …, 2011 - journals.plos.org
… The gD/Nectin-1 complex was crystallized by the vapor diffusion method with 1.0M Na 2
HPO 4 /KH 2 PO 4 pH 7.2 and 300mM NH 4 SO 4 as precipitating agents. SDS gels and N-…