[HTML][HTML] Integrating artificial with natural cells to translate chemical messages that direct E. coli behaviour

…, D Cecchi, J Fontana, M Marchioretto… - Nature …, 2014 - nature.com
Previous efforts to control cellular behaviour have largely relied upon various forms of genetic
engineering. Once the genetic content of a living cell is modified, the behaviour of that cell …

What planar lipid membranes tell us about the pore-forming activity of cholesterol-dependent cytolysins

M Marchioretto, M Podobnik, M Dalla Serra… - Biophysical …, 2013 - Elsevier
Pore-forming toxins are an important group of natural molecules that damage cellular
membranes by forming transmembrane pores. They are used by many organisms for attack or …

Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation

…, SW McKellar, KJ Nieken, M Marchioretto… - Elife, 2020 - elifesciences.org
By shaping gene expression profiles, small RNAs (sRNAs) enable bacteria to efficiently adapt
to changes in their environment. To better understand how Escherichia coli acclimatizes to …

Neuronal firing modulation by a membrane-targeted photoswitch

…, P Baldelli, MD Serra, L Lunelli, M Marchioretto… - Nature …, 2020 - nature.com
… decrease, generating hyperpolarization, followed by a slower C m increase at the light offset,
… In the simulation, we changed C m in time and calculated the predicted V m by keeping g …

[HTML][HTML] Plasticity of listeriolysin O pores and its regulation by pH and unique histidine

M Podobnik, M Marchioretto, M Zanetti, A Bavdek… - Scientific Reports, 2015 - nature.com
… of T m on pH reveals a bell-shaped profile for all LLO variants (Fig. 2C), with the highest T m
… bell shaped profile of T m versus pH similar to LLO, the absolute value of T m for these two …

SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy

…, A Rossi, D Donzel, M Clamer, M Marchioretto… - Nature cell …, 2020 - nature.com
The contribution of ribosome heterogeneity and ribosome-associated proteins to the molecular
control of proteomes in health and disease remains unclear. Here, we demonstrate that …

[HTML][HTML] Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes

SS Metkar, M Marchioretto, V Antonini… - Cell Death & …, 2015 - nature.com
Perforin-mediated cytotoxicity is an essential host defense, in which defects contribute to
tumor development and pathogenic disorders including autoimmunity and autoinflammation. …

Heavy metals extraction from anaerobically digested sludge

MM Marchioretto, H Bruning, NTP Loan… - Water Science and …, 2002 - iwaponline.com
This paper reports on the chemical extraction efficiency in the removal of heavy metals from
sludge from an activated-sludge system, which receives as influent both industrial and …

[PDF][PDF] Active ribosome profiling with RiboLace

…, F Lauria, P Bernabò, RF Gómez-Biagi, M Marchioretto… - Cell Reports, 2018 - cell.com
Ribosome profiling, or Ribo-seq, is based on large-scale sequencing of RNA fragments
protected from nuclease digestion by ribosomes. Thanks to its unique ability to provide …

Heavy metals precipitation in sewage sludge

MM Marchioretto, H Bruning… - Separation science and …, 2005 - Taylor & Francis
There is a great need for heavy metal removal from strongly metal‐polluted sewage sludges.
One of the advantages of heavy metal removal from this type of sludge is the possibility of …