Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis
remains out of control in several parts of the world including Africa and Asia. Although …

Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-based
methods being considered the gold standard for drug susceptibility testing, molecular …

… M. tuberculosis and the other members of the M. tuberculosis complex (MTBC) remain the
leading bacterial killers worldwide and still account for 1.3 million deaths annually 1 . Of major …

… Immunological assays could improve outcomes in populations in whom diagnosis is very
difficult, such as children in whom reports of the T-cell activation marker (TAM-TB) test suggest …

Background Molecular diagnostics are considered the most promising route to achievement
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex (MTBC…

… Such large SNP differences among isolates with identical IS6110 patterns in a low-incidence
setting is rather unexpected, as this has been considered a reliable marker for isolates …

Rapid diagnosis of drug-resistant tuberculosis is important in determining proper
management. This letter reports on limitations of the Xpert MTB/RIF assay in determining …

Background The risk of tuberculosis outbreaks among people fleeing hardship for refuge in
Europe is heightened. We describe the cross-border European response to an outbreak of …

… Solutions of 0.025, 0.05, 0.25, and 0.5 M persulfate were prepared containing one of the
probe compounds; each solution was adjusted to pH 12 using 5 M NaOH. All reactions were …

… As a sensitivity analysis, we also included CRP as a continuous marker in the model.
Finally, we performed a subgroup analysis limiting data to patients with a main diagnosis of …