Dexterous manipulation with a highly redundant movement system is one of the hallmarks
of human motor skills. From numerous behavioral studies, there is strong evidence that …

Schizophrenia is a serious psychiatric disorder with a broadly undiscovered genetic etiology.
Recent studies of de novo mutations (DNMs) in schizophrenia and autism have reinforced …

DNA replication−associated mutations are repaired by two components: polymerase
proofreading and mismatch repair. The mutation consequences of disruption to both repair …

Background: Projections of cancer incidence are important for planning health services and
to provide a baseline for assessing the impact of public health interventions. Methods: Rates …

Background Dahl salt-sensitive (Dahl S) rats exhibit many phenotypic traits associated with
salt-sensitive hypertension in man. Specifically, they are salt-sensitive, insulin-resistant and …

We present a control architecture for fast quadruped locomotion over rough terrain. We
approach the problem by decomposing it into many sub-systems, in which we apply state-of-the-…

Mammary gland development is controlled by a dynamic interplay between endocrine
hormones and locally produced factors. Biogenic monoamines (serotonin, dopamine, …

Purpose BRAF V600E is a potentially highly targetable mutation detected in a subset of
pediatric low-grade gliomas (PLGGs). Its biologic and clinical effect within this diverse group of …

Purpose To uncover the genetic events leading to transformation of pediatric low-grade
glioma (PLGG) to secondary high-grade glioma (sHGG). Patients and Methods We …

Clonal hematopoiesis results from enhanced fitness of a mutant hematopoietic stem and
progenitor cell (HSPC), but how such clones expand is unclear. We developed a technique that …