User profiles for M. Neset Özel
Mehmet Neset OzelNew York University Verified email at nyu.edu Cited by 901 |
[PDF][PDF] Serial synapse formation through filopodial competition for synaptic seeding factors
Following axon pathfinding, growth cones transition from stochastic filopodial exploration to
the formation of a limited number of synapses. How the interplay of filopodia and synapse …
the formation of a limited number of synapses. How the interplay of filopodia and synapse …
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly
…, MN Özel, I Papatheodorou, M Petkovic… - Science, 2022 - science.org
For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …
Neuronal diversity and convergence in a visual system developmental atlas
Deciphering how neuronal diversity is established and maintained requires a detailed
knowledge of neuronal gene expression throughout development. In contrast to mammalian …
knowledge of neuronal gene expression throughout development. In contrast to mammalian …
A complete temporal transcription factor series in the fly visual system
The brain consists of thousands of neuronal types that are generated by stem cells producing
different neuronal types as they age. In Drosophila, this temporal patterning is driven by …
different neuronal types as they age. In Drosophila, this temporal patterning is driven by …
Charcot-Marie-Tooth 2B mutations in rab7 cause dosage-dependent neurodegeneration due to partial loss of function
S Cherry, EJ Jin, MN Özel, Z Lu, E Agi, D Wang… - Elife, 2013 - elifesciences.org
10.7554/eLife.01064.001 The small GTPase Rab7 is a key regulator of endosomal maturation
in eukaryotic cells. Mutations in rab7 are thought to cause the dominant neuropathy …
in eukaryotic cells. Mutations in rab7 are thought to cause the dominant neuropathy …
Filopodial dynamics and growth cone stabilization in Drosophila visual circuit development
10.7554/eLife.10721.001 Filopodial dynamics are thought to control growth cone guidance,
but the types and roles of growth cone dynamics underlying neural circuit assembly in a …
but the types and roles of growth cone dynamics underlying neural circuit assembly in a …
[PDF][PDF] Live observation of two parallel membrane degradation pathways at axon terminals
Neurons are highly polarized cells that require continuous turnover of membrane proteins at
axon terminals to develop, function, and survive. Yet, it is still unclear whether membrane …
axon terminals to develop, function, and survive. Yet, it is still unclear whether membrane …
Coordinated control of neuronal differentiation and wiring by sustained transcription factors
The large diversity of cell types in nervous systems presents a challenge in identifying the
genetic mechanisms that encode it. Here, we report that nearly 200 distinct neurons in the …
genetic mechanisms that encode it. Here, we report that nearly 200 distinct neurons in the …
Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling
10.7554/eLife.01699.001 Axonal branching allows a neuron to connect to several targets,
increasing neuronal circuit complexity. While axonal branching is well described, the …
increasing neuronal circuit complexity. While axonal branching is well described, the …
A comprehensive series of temporal transcription factors in the fly visual system
…, L Dudragne, YC Chen, T Tran, AM Jaimes, MN Özel… - Biorxiv, 2021 - biorxiv.org
The brain consists of thousands of different neuronal types that are generated through multiple
divisions of neuronal stem cells. These stem cells have the capacity to generate different …
divisions of neuronal stem cells. These stem cells have the capacity to generate different …