User profiles for M. Notaras

Michael Notaras Ph.D.

Center for Neurogenetics, Weill Cornell Medical College of Cornell University
Verified email at med.cornell.edu
Cited by 1364

Neurobiology of BDNF in fear memory, sensitivity to stress, and stress-related disorders

M Notaras, M van den Buuse - Molecular psychiatry, 2020 - nature.com
Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy

M Notaras, R Hill, M van den Buuse - Molecular psychiatry, 2015 - nature.com
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …

A role for the BDNF gene Val66Met polymorphism in schizophrenia? A comprehensive review

M Notaras, R Hill, M Van den Buuse - Neuroscience & Biobehavioral …, 2015 - Elsevier
Schizophrenia is believed to arise from complex gene–environment interactions. Brain-derived
neurotrophic factor (BDNF) is involved in neuronal development, differentiation and …

[PDF][PDF] Lateral subcutaneous sphincterotomy for anal fissure—a new technique

MJ Notaras - 1969 - journals.sagepub.com
Results: As anticipated, the'key-hole'deformity was eliminated in all 66 patients treated. The
relief from pain was immediate and the fissures healed within three weeks. The incidence of …

[HTML][HTML] Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids

M Notaras, A Lodhi, F Dündar, P Collier… - Molecular …, 2022 - nature.com
Due to an inability to ethically access developing human brain tissue as well as identify
prospective cases, early-arising neurodevelopmental and cell-specific signatures of …

Brain-derived neurotrophic factor (BDNF): novel insights into regulation and genetic variation

M Notaras, M van den Buuse - The Neuroscientist, 2019 - journals.sagepub.com
Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that
now spans 35 years of research. While all neurotrophins share considerable overlap in …

The treatment of anal fissure by lateral subcutaneous internal sphincterotomy—a technique and results

MJ Notaras - British Journal of Surgery, 1971 - cir.nii.ac.jp
< jats: title> Abstract < jats: p> A technique of internal anal sphincterotomy for anal fissure by
the mid-lateral subcutaneous route is described. The operation avoids the “key-hole” …

A review of three popular methods of treatment of postanal (pilonidal) sinus disease

MJ Notaras - Journal of British Surgery, 1970 - academic.oup.com
Three popular surgical techniques for the treatment of postanal (pilonidal) sinus disease
have been evaluated. The lay-open technique appears to have several advantages over the …

[HTML][HTML] Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling

M Allen, BS Huang, MJ Notaras, A Lodhi… - Molecular …, 2022 - nature.com
The cellular mechanisms of autism spectrum disorder (ASD) are poorly understood.
Cumulative evidence suggests that abnormal synapse function underlies many features of this …

[HTML][HTML] The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors

M Notaras, A Lodhi, H Fang, D Greening… - Translational …, 2021 - nature.com
… An Orbitrap mass analyzer acquired Full MS scans over a range of 350-1500 m/z with
resolution 120,000 at m/z 200. The top 20 most-abundant precursors were selected with an …