Although much research in the 1960s and 1970s was devoted to cross-cultural issues such
as expatriate employment, researchers moved away from doing cross-cultural research in …

Bioluminescence is a ubiquitous imaging modality for visualizing biological processes in vivo.
This technique employs visible light and interfaces readily with most cell and tissue types, …

Signals from commensal bacteria can influence immune cell development and susceptibility
to infectious or inflammatory diseases. However, the mechanisms by which commensal …

In the original formulation of the micromechanical method of cells, designated for the analysis
of fibrous composites with periodic structure, the repeating volume element consists of four …

Chronic infections strain the regenerative capacity of antiviral T lymphocyte populations,
leading to failure in long-term immunity. The cellular and molecular events controlling this …

Background: Patients with chronic inflammatory disease (CID) treated with immunosuppressive
medications have increased risk for severe COVID-19. Although mRNA-based SARS-…

Dynamic reprogramming of metabolism is essential for T cell effector function and memory
formation. However, the regulation of metabolism in exhausted CD8 + T (Tex) cells is poorly …

Five general routes for the preparation of polyoxyethylene [generally referred to as poly(ethylene
glycol) or PEG] derivatives are described. These routes are (1) nucleophilic …

T cell exhaustion has a major role in failure to control chronic infection. High expression of
inhibitory receptors, including PD-1, and the inability to sustain functional T cell responses …

CD8+ T cells responding to intracellular infection give rise to cellular progeny that become
terminally differentiated effector cells and self-renewing memory cells. T-bet and …