… Citation: Oh SS, Galanter J, Thakur N, Pino-Yanes M, Barcelo NE, White MJ, et al. (2015)
Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled. PLoS Med 12(12) …

10.7554/eLife.20532.001 Populations are often divided categorically into distinct racial/ethnic
groups based on social rather than biological constructs. Genetic ancestry has been …

The African Diaspora in the Western Hemisphere represents one of the largest forced
migrations in history and had a profound impact on genetic diversity in modern populations. To …

… Author links open overlay panel Maria Pino-Yanes PhD a b , Neeta Thakur MD, MPH a ,
Christopher R. Gignoux PhD c , Joshua M. Galanter MD, MAS a c , Lindsey A. Roth MA a , …

Allergic rhinitis is the most common clinical presentation of allergy, affecting 400 million
people worldwide, with increasing incidence in westernized countries 1 , 2 . To elucidate the …

Rationale: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide.
There are significant racial/ethnic differences in albuterol drug response. Objectives: To …

Rationale: Stress is associated with asthma morbidity in Puerto Ricans (PRs), who have
reduced bronchodilator response (BDR). Objectives: To examine whether stress and/or a gene …

Asthma is a complex disease with sex-specific differences in prevalence. Candidate gene
studies have suggested that genotype-by-sex interaction effects on asthma risk exist, but this …

Background The Gly-to-Arg substitution at the 16 position (rs1042713) in the β 2 -adrenoceptor
gene (ADRB2) is associated with enhanced downregulation and uncoupling of β 2 -…

The indigenous population of the Canary Islands, which colonized the archipelago around
the 3 rd century CE, provides both a window into the past of North Africa and a unique model …