Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress

C Michiels, M Raes, O Toussaint, J Remacle - Free radical Biology and …, 1994 - Elsevier
Eukaryotic cells have to constantly cope with highly reactive oxygen-derived free radicals.
Their defense against these free radicals is achieved by natural antioxidant molecules but …

Is HIF-1α a pro-or an anti-apoptotic protein?

JP Piret, D Mottet, M Raes, C Michiels - Biochemical pharmacology, 2002 - Elsevier
Hypoxia-inducible factor-1 (HIF-1) is the major transcription factor specifically activated by
hypoxia. It induces the expression of different genes whose products play an adaptive role for …

Mitochondrial (dys) function in adipocyte (de) differentiation and systemic metabolic alterations

A De Pauw, S Tejerina, M Raes, J Keijer… - The American journal of …, 2009 - Elsevier
In mammals, adipose tissue, composed of BAT and WAT, collaborates in energy partitioning
and performs metabolic regulatory functions. It is the most flexible tissue in the body, …

Glutathione peroxidase, superoxide dismutase, and catalase inactivation by peroxides and oxygen derived free radicals

…, A Houbion, D Lambert, C Michiels, M Raes… - Mechanisms of ageing …, 1990 - Elsevier
… To 1 ml of TRAP buffer (20 raM, pH 9.0), containing 0.25 M sucrose and 2 mM EDTA, were
added successively 10/~1 of 0.1 M epinephrine, 20 ~1 of 0.1 M xanthine and 2 ~1 of xanthine …

[HTML][HTML] M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide

M Genin, F Clement, A Fattaccioli, M Raes, C Michiels - BMC cancer, 2015 - Springer
… Suspension was centrifuged 5 min at 200 g 4 C and the pellet resuspended with glycine 0.1
M (in cold PBS) and incubated 10 min at 4 C. A last centrifugation of 5 min at 200 g and 4 C …

Biological structures as a source of habitat heterogeneity and biodiversity on the deep ocean margins

…, H Gheerardyn, NJ King, M Raes - Marine …, 2010 - Wiley Online Library
… The depth range of banks in this region is from 50 to 200 m. The shelf break occurs at
depths between 200 and 400 m, while the abyssal plain is below 2400 m depth. The figure is …

[HTML][HTML] Exhausted parents: Development and preliminary validation of the parental burnout inventory

I Roskam, ME Raes, M Mikolajczak - Frontiers in psychology, 2017 - frontiersin.org
Can parents burn out? The aim of this research was to examine the construct validity of the
concept of parental burnout and to provide researchers which an instrument to measure it. …

Exhausted parents: Sociodemographic, child-related, parent-related, parenting and family-functioning correlates of parental burnout

M Mikolajczak, ME Raes, H Avalosse… - Journal of Child and …, 2018 - Springer
… Examples of items are “I’m usually able to find ways to control my emotions when I want to”
and “Generally, I find it difficult to know exactly what emotion I’m feeling (Reversed)” The …

[HTML][HTML] ERK activation upon hypoxia: involvement in HIF-1 activation

…, T Arnould, G Michel, I Roland, D Mottet, M Raes… - FEBS letters, 2000 - Elsevier
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor activated by hypoxia. The HIF-1
activation transduction pathway is poorly understood. In this report, we investigated the …

Development of a sensitive multi-well colorimetric assay for active NFκB

…, A Houbion, M Art, H Le Calvez, M Raes… - Nucleic acids …, 2001 - academic.oup.com
The transcription factor nuclear factor κB (NFκB) is a key factor in the immune response
triggered by a wide variety of molecules such as inflammatory cytokines, or some bacterial and …