A longitudinal follow-up of 550 mild cognitive impairment patients: evidence for large conversion to dementia rates and detection of major risk factors involved

…, A Mauleón, M Rosende-Roca… - Journal of …, 2013 - content.iospress.com
The most recent studies about mild cognitive impairment (MCI) are focused on the search
for factors that make patients more vulnerable to conversion to dementia, mainly Alzheimer’s …

Genome‐wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks …

…, O Maroñas, M RosendeRoca… - Alzheimer's & …, 2019 - Wiley Online Library
Introduction Large variability among Alzheimer's disease (AD) cases might impact genetic
discoveries and complicate dissection of underlying biological pathways. Methods Genome …

[HTML][HTML] Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive …

…, V Fernández, H Wagner, M Rosende-Roca… - Molecular …, 2017 - nature.com
Few data are available concerning the role of risk markers for Alzheimer’s disease (AD) in
progression to AD dementia among subjects with mild cognitive impairment (MCI). We …

[HTML][HTML] Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene

…, M Thelen, A Mauleón, M Rosende-Roca… - Translational …, 2014 - nature.com
To follow-up loci discovered by the International Genomics of Alzheimer’s Disease Project,
we attempted independent replication of 19 single nucleotide polymorphisms (SNPs) in a …

[HTML][HTML] The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease

…, J López-Arrieta, A Mauleón, M Rosende-Roca… - Genome medicine, 2011 - Springer
Background In order to identify novel loci associated with Alzheimer's disease (AD), we
conducted a genome-wide association study (GWAS) in the Spanish population. Methods We …

[HTML][HTML] Neuropsychiatric profiles and conversion to dementia in mild cognitive impairment, a latent class analysis

…, I Hernández, A Mauleón, M Rosende-Roca… - Scientific reports, 2021 - nature.com
Neuropsychiatric symptoms (NPS) have been recently addressed as risk factors of conversion
to Alzheimer’s disease (AD) and other dementia types in patients diagnosed with Mild …

[HTML][HTML] A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress

…, M Rosende-Roca, L Vargas, U Bojaryn, M Ricciardi… - Scientific Reports, 2023 - nature.com
… The mean BMI at baseline was 28 kg/m 2 , the mean systolic pressure was 137 mmHg, and
the mean diastolic pressure was 80 mmHg. The body mass composition characteristics of …

[HTML][HTML] Dementia care in times of COVID-19: Experience at Fundació ACE in Barcelona, Spain

…, I Rodríguez, M Rosende-Roca… - Journal of …, 2020 - content.iospress.com
Background: Fundació ACE is a non-profit organization providing care based on a holistic
model to persons with cognitive disorders and their families for 25 years in Barcelona, Spain. …

[HTML][HTML] ATP5H/KCTD2 locus is associated with Alzheimer's disease risk

…, JJ Galán, JC Bis, A Mauleón, M Rosende-Roca… - Molecular …, 2014 - nature.com
To identify loci associated with Alzheimer disease, we conducted a three-stage analysis
using existing genome-wide association studies (GWAS) and genotyping in a new sample. In …

[HTML][HTML] Usefulness of peripapillary nerve fiber layer thickness assessed by optical coherence tomography as a biomarker for Alzheimer's disease

…, I Hernández, C Abdelnour, M Rosende-Roca… - Scientific reports, 2018 - nature.com
The use of optical coherence tomography (OCT) has been suggested as a potential biomarker
for Alzheimer’s Disease based on previously reported thinning of the retinal nerve fiber …