User profiles for M. Saarma
 | Mart Saarmaprofessor, University of Helsinki Verified email at helsinki.fi Cited by 34727 |
The GDNF family: signalling, biological functions and therapeutic value
MS Airaksinen, M Saarma - Nature Reviews Neuroscience, 2002 - nature.com
Members of the nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF)
families — comprising neurotrophins and GDNF-family ligands (GFLs), respectively — …
families — comprising neurotrophins and GDNF-family ligands (GFLs), respectively — …
GDNF family neurotrophic factor signaling: four masters, one servant?
MS Airaksinen, A Titievsky, M Saarma - Molecular and Cellular …, 1999 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF), and related factors neurturin (NTN), artemin
(ART), and persephin (PSP), are members of the GDNF family of neurotrophic factors (Fig. …
(ART), and persephin (PSP), are members of the GDNF family of neurotrophic factors (Fig. …
Novel functions and signalling pathways for GDNF
H Sariola, M Saarma - Journal of cell science, 2003 - journals.biologists.com
… 3) (reviewed by Sariola and Saarma, 1999). Metanephric development is initiated in 61%
of RET-deficient embryos (Schuchardt et al., 1994), which suggests that other, non-Ret …
of RET-deficient embryos (Schuchardt et al., 1994), which suggests that other, non-Ret …
Regulation of cell fate decision of undifferentiated spermatogonia by GDNF
The molecular control of self-renewal and differentiation of stem cells has remained enigmatic.
Transgenic loss-of-function and overexpression models now show that the dosage of glial …
Transgenic loss-of-function and overexpression models now show that the dosage of glial …
The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
… The intracellular sharp microelectrodes were filled with 3 M potassium methylsulphate plus
10 mM KCl, or with a mixture of potassium methylsulphate (3 M) and potassium acetate (2 M) …
10 mM KCl, or with a mixture of potassium methylsulphate (3 M) and potassium acetate (2 M) …
Functional receptor for GDNF encoded by the c-ret proto-oncogene
…, V Pachnis, U Arumäe, H Sariola, M Saarma… - Nature, 1996 - nature.com
… The locustwine is an established regulator of M-phase progression. The similarity in phenotype
between boule and twine suggests that boule, and by analogy DAZ in humans, controls …
between boule and twine suggests that boule, and by analogy DAZ in humans, controls …
GDNF signalling through the Ret receptor tyrosine kinase
… Similar analysis indicated that Xenopus oocytes injected with GDNF RNA express a protein
of M, 20K, in good agreement with the predicted size of mature GDNF". bj, Coexpression of …
of M, 20K, in good agreement with the predicted size of mature GDNF". bj, Coexpression of …
[HTML][HTML] Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
Psychedelics produce fast and persistent antidepressant effects and induce neuroplasticity
resembling the effects of clinically approved antidepressants. We recently reported that …
resembling the effects of clinically approved antidepressants. We recently reported that …
Defects in enteric innervation and kidney development in mice lacking GDNF
…, J Drago, A Grinberg, EJ Lee, SP Huang, M Saarma… - Nature, 1996 - nature.com
GLIAL-CELL-LINE-DERIVED neurotrophic factor (GDNF) has been isolated as a neurotrophic
factor for midbrain dopaminergic neurons 1 . Because of its neurotrophic activity on a wide …
factor for midbrain dopaminergic neurons 1 . Because of its neurotrophic activity on a wide …
Multiple promoters direct tissue-specific expression of the rat BDNF gene
… M HCI for IO min, acetylated for 20 min with 0.25% acetic anhydride in 0.1 M ethanolamine,
… C for40 min, treated with RNAase (10 ug/ml) in 0.5 M NaCI, 20 mM Tris-HCI (pH 7.5), 2 mM …
… C for40 min, treated with RNAase (10 ug/ml) in 0.5 M NaCI, 20 mM Tris-HCI (pH 7.5), 2 mM …