… c | x and y coordinates of a single molecule (x m , y m ) can be computed with high precision
… The mesh surface (top) shows a Gaussian model of the PSF centred on (x m , y m ). d | …

Microbial production of organic acids is a promising approach for obtaining building-block
chemicals from renewable carbon sources. Although some acids have been produced for …

Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that restricts
the optical resolution to roughly 250 nm and was previously thought to be impenetrable. …

… ., Kasper, R., Seefeldt, B., Mukherjee, A., Tinnefeld, P., Sauer, M.: Subdiffraction-resolution
fluorescence imaging with conventional fluorescent probes. ANGEWANDTE CHEMIE-…

… M) and much higher maximum rate of the reaction (V max = 4.1 × 10 −… AK, M. Sauer, FPF
and JPFA performed enhanced microscopy experiments. All authors read and agreed on the …

… PIN1 polar localization (H–J, M, and N). GFP signals in green (A, C–E, and N). IAA signal
in brown (B) and PIN1 signal in red (H–J, and M). Nuclear counterstain in blue (H–J, and M). …

Background All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for
acute promyelocytic leukemia (APL), resulting in cure rates exceeding 80%. Pilot studies of …

Background The molecular cause of inflammatory bowel disease is largely unknown. Methods
We performed genetic-linkage analysis and candidate-gene sequencing on samples from …

Axis formation occurs in plants, as in animals, during early embryogenesis. However, the
underlying mechanism is not known. Here we show that the first manifestation of the apical–…

… To avoid nonspecific adsorption of fluorophores on the cover glass, it is recommended to
coat it with glycine (2 M glycine solution for 30–60 min) before use. Transfect ∼2 × 10 6 cells, …