Cytochromes P450 (CYP) are a major source of variability in drug pharmacokinetics and
response. Of 57 putatively functional human CYPs only about a dozen enzymes, belonging to …

Accumulating research shows that prenatal exposure to maternal stress increases the risk for
behavioral and mental health problems later in life. This review systematically analyzes the …

For many decades, the inability of lesioned central neurons to regrow was accepted almost
as a "law of nature", and on the clinical level, spinal cord and brain lesions were seen as …

The purpose of this study was to develop a method of classifying cancers to specific diagnostic
categories based on their gene expression signatures using artificial neural networks (…

Recent years have witnessed many breakthroughs in research on graphene (the first two-dimensional
atomic crystal) as well as a significant advance in the mass production of this …

A domain of DNA designated N-myc is amplified 20- to 140-fold in human neuroblastoma
cell lines but not in cell lines from other tumor types. N-myc has now been found to be …

The capacity of the adult brain and spinal cord to repair lesions by axonal regeneration or
compensatory fibre growth is extremely limited. A monoclonal antibody (IN-1) raised against NI…

Amplified cellular genes in mammalian cells frequently manifest themselves as double minute
chromosomes (DMs) and homogeneously staining regions of chromosomes (HSRs) 1,2 . …

Background: Mutations in NOD2, a putative intracellular receptor for bacterial peptidoglycans,
are associated with a subset of Crohn’s disease but the molecular mechanism linking this …

Objectives : We sought to test the hypothesis that complex fractionated electrograms (CFAEs)
recorded during atrial fibrillation (AF) could be used as target sites for catheter ablation of …