Covamof: A framework for modeling variability in software product families

M Sinnema, S Deelstra, J Nijhuis, J Bosch - Software Product Lines: Third …, 2004 - Springer
A key aspect of variability management in software product families is the explicit representation
of the variability. Experiences at several industrial software development companies …

Product derivation in software product families: a case study

S Deelstra, M Sinnema, J Bosch - Journal of Systems and Software, 2005 - Elsevier
From our experience with several organizations that employ software product families, we
have learned that, contrary to popular belief, deriving individual products from shared software …

Classifying variability modeling techniques

M Sinnema, S Deelstra - Information and software technology, 2007 - Elsevier
Variability modeling is important for managing variability in software product families, especially
during product derivation. In the past few years, several variability modeling techniques …

Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia

…, MS Reuter, P Rump, R Segel, M Sinnema, M Smith… - Nature …, 2017 - nature.com
Histone lysine methylation, mediated by mixed-lineage leukemia (MLL) proteins, is now
known to be critical in the regulation of gene expression, genomic stability, cell cycle and …

Dementia in older adults with intellectual disabilities—epidemiology, presentation, and diagnosis

…, N Bass, M Sinnema, M Maaskant - Journal of Policy and …, 2010 - Wiley Online Library
As life expectancy of people with intellectual disabilities (ID) extends into older age, dementia
is an increasing cause of morbidity and mortality. To update and summarize current …

VxBPEL: Supporting variability for Web services in BPEL

M Koning, C Sun, M Sinnema, P Avgeriou - Information and Software …, 2009 - Elsevier
Web services provide a way to facilitate the business integration over the Internet. Flexibility
is an important and desirable property of Web service-based systems due to dynamic …

[PDF][PDF] De novo mutations in SON disrupt RNA splicing of genes essential for brain development and metabolism, causing an intellectual-disability syndrome

…, JK Stone, EY Park, JA Veltman, M Sinnema… - The American Journal of …, 2016 - cell.com
The overall understanding of the molecular etiologies of intellectual disability (ID) and
developmental delay (DD) is increasing as next-generation sequencing technologies identify …

Physical health problems in adults with Prader–Willi syndrome

M Sinnema, MA Maaskant… - American Journal of …, 2011 - Wiley Online Library
Prader–Willi syndrome (PWS) is a genetic disorder which is characterized by severe
hypotonia and feeding problems in early infancy. In later childhood and adolescence, this is …

Psychiatric illness in a cohort of adults with Prader-Willi syndrome

M Sinnema, H Boer, P Collin, MA Maaskant… - Research in …, 2011 - Elsevier
Previous studies have suggested an association between PWS and comorbid psychiatric
illness. Data on prevalence rates of psychopathology is still scarce. This paper describes a …

Experiences in software product families: Problems and issues during product derivation

S Deelstra, M Sinnema, J Bosch - … , SPLC 2004, Boston, MA, USA, August …, 2004 - Springer
… More related work and an elaborate description of the generic process are provided by
Deelstra, Sinnema, and Bosch [12]. The problems with implicit properties confirm problems …