The objective of this study was to determine the impact of lupus nephritis disease activity on
maternal and foetal outcomes in pregnant patients with systemic lupus erythematosus (SLE). …

Introduction Major clinically relevant inflammatory events such as septic shock and severe
COVID-19 trigger dynamic changes in the host immune system, presenting promising …

Sepsis is a clinical syndrome characterized by a dysregulated response to infection. It
represents a leading cause of mortality in ICU patients worldwide. Although sepsis is in the point …

Although the link between microbial infections and Alzheimer's disease (AD) has been
demonstrated in multiple studies, the involvement of pathogens in the development of AD …

Ideal cardiovascular health (CVH) is defined for the presence of ideal behavioral and health
metrics known to prevent cardiovascular disease (CVD). The association of circulatory …

Septic shock is a major cause of mortality in ICU patients, its pathophysiology is complex
and not properly understood. Oxidative stress seems to be one of the most important …

Acute kidney injury (AKI) is associated with impaired outcomes in critically ill COVID-19
patients. However, the prognostic significance of early AKI is poorly described. We aimed to …

Assessment of the cerebral microcirculation by on-line visualization has been impossible for
a long time. Sidestream dark-field (SDF) imaging is a relatively new method allowing direct …

The purpose of our study was to evaluate changes of the cerebral microcirculation during
the early stages of endotoxemia in mechanically-ventilated rabbits using Sidestream dark-field …

… The hematocrit \(\varphi \) represents the volume fraction of erythrocytes in the blood, \(\varphi
\) m is the maximum possible volume fraction of erythrocytes (maximal packing density). In …