The dose makes the poison: nutritional overload determines the life traits of blood-feeding arthropods
M Sterkel, JHM Oliveira, V Bottino-Rojas… - Trends in …, 2017 - cell.com
Vertebrate blood composition is heavily biased towards proteins, and hemoglobin, which is
a hemeprotein, is by far the most abundant protein. Typically, hematophagous insects ingest …
a hemeprotein, is by far the most abundant protein. Typically, hematophagous insects ingest …
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
…, M Souza-Gomes, M Sterkel… - Proceedings of the …, 2015 - National Acad Sciences
Rhodnius prolixus not only has served as a model organism for the study of insect physiology,
but also is a major vector of Chagas disease, an illness that affects approximately seven …
but also is a major vector of Chagas disease, an illness that affects approximately seven …
Comparing treatment intensities of tactile-thermal application
…, K Dong, MT Rau, TE Prescott, AM Lloyd, MT Sterkel… - Dysphagia, 1998 - Springer
The purpose of this study was to investigate the relationships of four intensities of tactile-thermal
application (TTA) to changes in duration of stage transition (DST) and performance on a …
application (TTA) to changes in duration of stage transition (DST) and performance on a …
Scaling properties of the tunneling field effect transistor (TFET): Device and circuit
…, J Fischer, M Fulde, A Bargagli-Stoffi, M Sterkel… - Solid-state …, 2006 - Elsevier
The scaling properties of the tunneling field effect transistor (TFET) are shown using standard
130nm, 90nm, and 65nm CMOS process flows. For the different technology nodes the …
130nm, 90nm, and 65nm CMOS process flows. For the different technology nodes the …
Neuropeptide precursor gene discovery in the Chagas disease vector Rhodnius prolixus
We show a straightforward workflow combining homology search in Rhodnius prolixus genome
sequence with cloning by rapid amplification of cDNA ends and mass spectrometry. We …
sequence with cloning by rapid amplification of cDNA ends and mass spectrometry. We …
[PDF][PDF] Tyrosine detoxification is an essential trait in the life history of blood-feeding arthropods
M Sterkel, HD Perdomo, MG Guizzo, ABF Barletta… - Current Biology, 2016 - cell.com
… Sterkel et al. show that blood digestion by blood-sucking insects produces toxic amounts
of tyrosine, and that detoxification of an excess of this amino acid is an adaptation to a blood-…
of tyrosine, and that detoxification of an excess of this amino acid is an adaptation to a blood-…
Identification of G protein coupled receptors for opsines and neurohormones in Rhodnius prolixus. Genomic and transcriptomic analysis
The importance of Chagas disease motivated the scientific effort to obtain the complete
genomic sequence of the vector species Rhodnius prolixus, this information is also relevant to …
genomic sequence of the vector species Rhodnius prolixus, this information is also relevant to …
Identification of a point mutation associated with pyrethroid resistance in the para-type sodium channel of Triatoma infestans, a vector of Chagas' disease
J Fabro, M Sterkel, N Capriotti… - Infection, Genetics and …, 2012 - Elsevier
… Amino acid residue numbers are indicated using the sodium channel of M. domestica as a
… M indicates the position of the standard size marker, in which the lower five bands are 100, …
… M indicates the position of the standard size marker, in which the lower five bands are 100, …
Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
… In order to quantify the ecdysteroid levels, a serial dilution (ranging from 1028 M to 10212
M) of 20E was placed on each 96-well plate. Results were determined by comparison with …
M) of 20E was placed on each 96-well plate. Results were determined by comparison with …
OKB, a novel family of brain-gut neuropeptides from insects
M Sterkel, PL Oliveira, H Urlaub… - Insect biochemistry and …, 2012 - Elsevier
… Spectra in MS were recorded between 600 and 4000 m/z. Job-wide interpretation of the
MS data allowed the 15 highest peptides in intensity (with signal to noise ratios ≥30) for …
MS data allowed the 15 highest peptides in intensity (with signal to noise ratios ≥30) for …