Non-genetic mechanisms have recently emerged as important drivers of cancer therapy
failure 1 , where some cancer cells can enter a reversible drug-tolerant persister state in …

Stroma is a poorly defined non-parenchymal component of virtually every organ with key roles
in organ development, homeostasis, and repair. Studies of the bone marrow stroma have …

… viscosity that is much lower than the macroscopic viscosity η m . On the contrary, probes with
r p ≫ R h experience a viscosity equal to η m . It is noteworthy that the value of the diffusion …

T cell immunoglobulin and mucin-containing molecule 3 (TIM-3), first identified as a molecule
expressed on interferon-γ producing T cells 1 , is emerging as an important immune-…

Understanding the molecular programs that guide differentiation during development is a
major challenge. Here, we introduce Waddington-OT, an approach for studying developmental …

Definitive haematopoiesis in the fetal liver supports self-renewal and differentiation of
haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly defined in …

This paper deals with the recent phenomenological model of the motion of nanoscopic objects
(colloidal particles, proteins, nanoparticles, molecules) in complex liquids. We analysed …

Haematopoiesis in the bone marrow (BM) maintains blood and immune cell production
throughout postnatal life. Haematopoiesis first emerges in human BM at 11–12 weeks after …

… For simplicity, let us assume that we only have one biological group with m batches, and
each batch j has n j cells. We model the log[gene expression] level of gene g at batch j’s ith cell …

… New capillaries were conditioned by passing a 0.1 M NaOH solution for 20 min and then …
The overlap concentration is given by x* = M p /(4/3 πR g 3 N A ), where M p is the molar …