User profiles for M. Taschuk

Morgan Taschuk

Ontario Institute for Cancer Research
Verified email at oicr.on.ca
Cited by 1399

[HTML][HTML] Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

…, A Gackowska, R Anderson, M Taschuk… - Nature …, 2012 - nature.com
Telomeres are specialized nucleoprotein structures, which protect chromosome ends and
have been implicated in the ageing process. Telomere shortening has been shown to …

[BOOK][B] Glancing angle deposition of thin films: engineering the nanoscale

MM Hawkeye, MT Taschuk, MJ Brett - 2014 - books.google.com
This book provides a highly practical treatment of Glancing Angle Deposition (GLAD), a thin
film fabrication technology optimized to produce precise nanostructures from a wide range of …

[HTML][HTML] Sentieon DNASeq variant calling workflow demonstrates strong computational performance and accuracy

…, CA Ross, M Taschuk, ED Wieben, M Wiepert… - Frontiers in …, 2019 - frontiersin.org
As reliable, efficient genome sequencing becomes ubiquitous, the need for similarly reliable
and efficient variant calling becomes increasingly important. The Genome Analysis Toolkit (…

Glancing angle deposition

MT Taschuk, MM Hawkeye, MJ Brett - Handbook of Deposition …, 2010 - Elsevier
Publisher Summary This chapter focuses on experimental aspects of the Glancing angle
deposition (GLAD) technique – its methods and possibilities. It introduces the basic theory, and …

Nanostructured metal oxide thin films for humidity sensors

JJ Steele, MT Taschuk, MJ Brett - IEEE Sensors Journal, 2008 - ieeexplore.ieee.org
… Steele and MT Taschuk are with the Department of Electrical and Com… Cross-sectional SEM
image of 1.5 m thick TiO GLAD film deposited onto … All films were 1:5 6 0:1 m thick and de- …

[HTML][HTML] Simulating next-generation sequencing datasets from empirical mutation and sequencing models

ZD Stephens, ME Hudson, LS Mainzer, M Taschuk… - PloS one, 2016 - journals.plos.org
An obstacle to validating and benchmarking methods for genome analysis is that there are
few reference datasets available for which the “ground truth” about the mutational landscape …

Detection of lead in water using laser-induced breakdown spectroscopy and laser-induced fluorescence

SL Lui, Y Godwal, MT Taschuk, YY Tsui… - Analytical …, 2008 - ACS Publications
Laser-induced breakdown spectroscopy (LIBS) is a well-known technique for fast, stand-off,
and nondestructive analysis of the elemental composition of a sample. We have been …

[HTML][HTML] Ten simple rules for making research software more robust

M Taschuk, G Wilson - PLoS computational biology, 2017 - journals.plos.org
Software produced for research, published and otherwise, suffers from a number of common
problems that make it difficult or impossible to run outside the original institution or even off …

Surface area characterization of obliquely deposited metal oxide nanostructured thin films

KM Krause, MT Taschuk, KD Harris, DA Rider… - Langmuir, 2010 - ACS Publications
The glancing angle deposition (GLAD) technique is used to fabricate nanostructured thin
films with high surface area. Quantifying this property is important for optimizing GLAD-based …

[HTML][HTML] Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects

…, AP Banks, HP Ngo, L Maringele, M Taschuk… - PLoS …, 2011 - journals.plos.org
To better understand telomere biology in budding yeast, we have performed systematic
suppressor/enhancer analyses on yeast strains containing a point mutation in the essential …