User profiles for M. Tomkova

Markéta Tomková

- Verified email at ludwig.ox.ac.uk - Cited by 1195

Mária Tomková

- Verified email at upjs.sk - Cited by 70

[HTML][HTML] Applications of nanocellulose/nanocarbon composites: Focus on biotechnology and medicine

L Bacakova, J Pajorova, M Tomkova, R Matejka, A Broz… - Nanomaterials, 2020 - mdpi.com
Nanocellulose/nanocarbon composites are newly emerging smart hybrid materials containing
cellulose nanoparticles, such as nanofibrils and nanocrystals, and carbon nanoparticles, …

[HTML][HTML] Transforming machine translation: a deep learning system reaches news translation quality comparable to human professionals

M Popel, M Tomkova, J Tomek, Ł Kaiser… - Nature …, 2020 - nature.com
The quality of human translation was long thought to be unattainable for computer translation
systems. In this study, we present a deep-learning system, CUBBITT, which challenges this …

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

…, G Velikova, Y Bi, F Yuan, M Tomkova… - Nature …, 2019 - nature.com
… ) was dissolved in 187 µl of DMSO to give around a 3.26 M solution. For each reaction, 25
µl of pic-borane solution and 5 µl of 3 M sodium acetate solution (pH 5.2, Thermo Fisher) were …

Identification, characterization, and engineering of glycosylation in thrombolyticsa

…, V Slonkova, J Mican, A Urminsky, M Tomkova… - Biotechnology …, 2023 - Elsevier
Cardiovascular diseases, such as myocardial infarction, ischemic stroke, and pulmonary
embolism, are the most common causes of disability and death worldwide. Blood clot hydrolysis …

DNA modifications: naturally more error prone?

M Tomkova, B Schuster-Böckler - Trends in Genetics, 2018 - cell.com
… Marketa Tomkova … The positions at which the major and minor grooves face the histone
surface are indicated by M and m. The crystal structures were rendered with NGL Viewer …

[PDF][PDF] Expression of Idh1R132H in the murine subventricular zone stem cell niche recapitulates features of early gliomagenesis

…, D Krell, P Brazauskas, K Al-Qahtani, M Tomkova… - Cancer cell, 2016 - cell.com
Isocitrate dehydrogenase 1 mutations drive human gliomagenesis, probably through
neomorphic enzyme activity that produces D-2-hydroxyglutarate. To model this disease, we …

[HTML][HTML] Mutational signature distribution varies with DNA replication timing and strand asymmetry

M Tomkova, J Tomek, S Kriaucionis… - Genome biology, 2018 - Springer
… The vector m LD of length 96 contains mutations on the leading strand (again normalized
by trinucleotides in leading strand/whole genome), and similarly m LG contains mutations from …

[PDF][PDF] Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma

…, CR Puig, P Siejka-Zielińska, C Song, M Tomkova… - Cancer Cell, 2023 - cell.com
For inoperable esophageal adenocarcinoma (EAC), identifying patients likely to benefit from
recently approved immunochemotherapy (ICI+CTX) treatments remains a key challenge. …

Determinants of heritable gene silencing for KRAB-dCas9+ DNMT3 and Ezh2-dCas9+ DNMT3 hit-and-run epigenome editing

H O'Geen, M Tomkova, JA Combs… - Nucleic acids …, 2022 - academic.oup.com
Precision epigenome editing has gained significant attention as a method to modulate gene
expression without altering genetic information. However, a major limiting factor has been …

Cellulose mesh with charged nanocellulose coatings as a promising carrier of skin and stem cells for regenerative applications

…, M Hannula, P Lahtinen, M Tomkova… - …, 2020 - ACS Publications
Engineering artificial skin constructs is an ongoing challenge. An ideal material for hosting
skin cells is still to be discovered. A promising candidate is low-cost cellulose, which is …