Perinatal oxygen in the developing lung
ER Vogel, RD Britt Jr, MC Trinidad… - Canadian journal of …, 2015 - cdnsciencepub.com
Lung diseases, such as bronchopulmonary dysplasia (BPD), wheezing, and asthma, remain
significant causes of morbidity and mortality in the pediatric population, particularly in the …
significant causes of morbidity and mortality in the pediatric population, particularly in the …
[PDF][PDF] Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells
CRISPR-Cas9 genome editing has enabled advanced T cell therapies, but occasional loss
of the targeted chromosome remains a safety concern. To investigate whether Cas9-induced …
of the targeted chromosome remains a safety concern. To investigate whether Cas9-induced …
[HTML][HTML] Precise transcript targeting by CRISPR-Csm complexes
D Colognori, M Trinidad, JA Doudna - Nature biotechnology, 2023 - nature.com
Robust and precise transcript targeting in mammalian cells remains a difficult challenge using
existing approaches due to inefficiency, imprecision and subcellular compartmentalization…
existing approaches due to inefficiency, imprecision and subcellular compartmentalization…
A bibliometric analysis of gamification research
Gamification has rapidly emerged as one of the favorite persuasive technologies widely used
with the aim of promoting a positive change in the user's behavior by means of including …
with the aim of promoting a positive change in the user's behavior by means of including …
[HTML][HTML] Structural factors that mediate scleral stiffness
…, JC Lotz, SM Lee, ML Trinidad… - … & visual science, 2008 - iovs.arvojournals.org
purpose. The intent of this study was to correlate measures of structurally relevant biochemical
constituents with tensile mechanical behavior in porcine and human posterior sclera. …
constituents with tensile mechanical behavior in porcine and human posterior sclera. …
Improved genome editing by an engineered CRISPR-Cas12a
CRISPR-Cas12a is an RNA-guided, programmable genome editing enzyme found within
bacterial adaptive immune pathways. Unlike CRISPR-Cas9, Cas12a uses only a single …
bacterial adaptive immune pathways. Unlike CRISPR-Cas9, Cas12a uses only a single …
[HTML][HTML] In vivo human T cell engineering with enveloped delivery vehicles
…, CR Sandoval Espinoza, MH Kang, M Trinidad… - Nature …, 2024 - nature.com
Viruses and virally derived particles have the intrinsic capacity to deliver molecules to cells,
but the difficulty of readily altering cell-type selectivity has hindered their use for therapeutic …
but the difficulty of readily altering cell-type selectivity has hindered their use for therapeutic …
Large proper motions in the jet of the high-mass YSO Cepheus A HW2
Using high angular resolution (~ 0 farcs 25-0 farcs 05) Very Large Array (VLA) observations
made at 3.6 cm, 1.3 cm, and 7 mm during the period 1991-2004, we report the detection of …
made at 3.6 cm, 1.3 cm, and 7 mm during the period 1991-2004, we report the detection of …
[HTML][HTML] Factors associated with surgical site infection after lower extremity bypass in the Society for Vascular Surgery (SVS) Vascular Quality Initiative (VQI)
JA Kalish, A Farber, K Homa, M Trinidad, A Beck… - Journal of vascular …, 2014 - Elsevier
Background Surgical site infection (SSI) is a major source of morbidity after infrainguinal
lower extremity bypass (LEB). This study examines processes of care associated with in-…
lower extremity bypass (LEB). This study examines processes of care associated with in-…
Decorating chromatin for enhanced genome editing using CRISPR-Cas9
…, M Trinidad, M Saffari Doost… - Proceedings of the …, 2022 - National Acad Sciences
CRISPR-associated (Cas) enzymes have revolutionized biology by enabling RNA-guided
genome editing. Homology-directed repair (HDR) in the presence of donor templates is …
genome editing. Homology-directed repair (HDR) in the presence of donor templates is …