User profiles for M. Ueffing

Marius Ueffing

Prof. Dr. rer. nat., Director, Institute for Ophthalmic Research, University of Tuebingen
Verified email at uni-tuebingen.de
Cited by 21082

[HTML][HTML] A new perspective on lipid research in age-related macular degeneration

…, M Biarnés, PJ Luthert, M Ueffing… - Progress in retinal and …, 2018 - Elsevier
There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

[HTML][HTML] A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

…, JW Miller, CA Toth, M Ueffing, M Zarbin… - Nature …, 2019 - nature.com
Age-related macular degeneration (AMD) is the most common cause of blindness among
the elderly in the developed world. While treatment is effective for the neovascular or “wet” …

[HTML][HTML] The complement system in age-related macular degeneration

A Armento, M Ueffing, SJ Clark - Cellular and Molecular Life Sciences, 2021 - Springer
Age-related macular degeneration (AMD) is a chronic and progressive degenerative disease
of the retina, which culminates in blindness and affects mainly the elderly population. AMD …

[HTML][HTML] Prevalence of age-related macular degeneration in Europe: the past and the future

…, E Nogoceke, T Peto, FM Pool, E Rodríguez, M Ueffing… - Ophthalmology, 2017 - Elsevier
Purpose Age-related macular degeneration (AMD) is a frequent, complex disorder in elderly
of European ancestry. Risk profiles and treatment options have changed considerably over …

[HTML][HTML] Latent membrane protein 1 of Epstein–Barr virus mimics a constitutively active receptor molecule

O Gires, U Zimber‐Strobl, R Gonnella, M Ueffing… - The EMBO …, 1997 - embopress.org
Latent membrane protein 1 (LMP1) of Epstein–Barr virus (EBV) is an integral membrane
protein which has transforming potential and is necessary but not sufficient for B‐cell …

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

…, W Kolch, H Prokisch, M Ueffing - Human molecular …, 2006 - academic.oup.com
… lysed in 50 mm Tris–HCl pH 7.4, 150 mm NaCl, 0.5% Nonidet P-40, protease inhibitors and
1 mm … Protein baits were eluted with desthiobiotin (2 mm in TBS). The eluates were used for …

Third-generation femtosecond technology

…, CY Teisset, M Schultze, S Prinz, M Haefner, M Ueffing… - Optica, 2014 - opg.optica.org
Femtosecond pulse generation was pioneered four decades ago using mode-locked dye
lasers, which dominated the field for the following 20 years. Dye lasers were then replaced …

[HTML][HTML] Latent membrane protein 1 of Epstein–Barr virus interacts with JAK3 and activates STAT proteins

…, C Kaiser, R Zeidler, B Scheffer, M Ueffing… - The EMBO …, 1999 - embopress.org
Latent membrane protein 1 (LMP1) acts like a permanently activated receptor of the tumor
necrosis factor (TNF)‐receptor superfamily and is absolutely required for B cell …

Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB

A Dumont, SP Hehner, TG Hofmann, M Ueffing… - Oncogene, 1999 - nature.com
Reactive oxygen species (ROS) play an important role in cell death induced by many different
stimuli. This study shows that hydrogen peroxide-induced apoptosis in T-cells did not …

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

…, M Matteoli, C Sala, M Ueffing - Journal of …, 2011 - Soc Neuroscience
… 124 mm NaCl, 5 mm KCl, 2 mm MgCl 2 , 30 mm glucose, 25 mm HEPES, pH 7.4, and 2 mm
or in Tyrode's solution containing 50 mm KCl or 2 μm TTX or 0.5 m sucrose. After fixation and …