User profiles for M. Ueffing
Marius UeffingProf. Dr. rer. nat., Director, Institute for Ophthalmic Research, University of Tuebingen Verified email at uni-tuebingen.de Cited by 21082 |
[HTML][HTML] A new perspective on lipid research in age-related macular degeneration
There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …
[HTML][HTML] A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration
Age-related macular degeneration (AMD) is the most common cause of blindness among
the elderly in the developed world. While treatment is effective for the neovascular or “wet” …
the elderly in the developed world. While treatment is effective for the neovascular or “wet” …
[HTML][HTML] The complement system in age-related macular degeneration
Age-related macular degeneration (AMD) is a chronic and progressive degenerative disease
of the retina, which culminates in blindness and affects mainly the elderly population. AMD …
of the retina, which culminates in blindness and affects mainly the elderly population. AMD …
[HTML][HTML] Prevalence of age-related macular degeneration in Europe: the past and the future
Purpose Age-related macular degeneration (AMD) is a frequent, complex disorder in elderly
of European ancestry. Risk profiles and treatment options have changed considerably over …
of European ancestry. Risk profiles and treatment options have changed considerably over …
[HTML][HTML] Latent membrane protein 1 of Epstein–Barr virus mimics a constitutively active receptor molecule
Latent membrane protein 1 (LMP1) of Epstein–Barr virus (EBV) is an integral membrane
protein which has transforming potential and is necessary but not sufficient for B‐cell …
protein which has transforming potential and is necessary but not sufficient for B‐cell …
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity
… lysed in 50 mm Tris–HCl pH 7.4, 150 mm NaCl, 0.5% Nonidet P-40, protease inhibitors and
1 mm … Protein baits were eluted with desthiobiotin (2 mm in TBS). The eluates were used for …
1 mm … Protein baits were eluted with desthiobiotin (2 mm in TBS). The eluates were used for …
Third-generation femtosecond technology
…, CY Teisset, M Schultze, S Prinz, M Haefner, M Ueffing… - Optica, 2014 - opg.optica.org
Femtosecond pulse generation was pioneered four decades ago using mode-locked dye
lasers, which dominated the field for the following 20 years. Dye lasers were then replaced …
lasers, which dominated the field for the following 20 years. Dye lasers were then replaced …
[HTML][HTML] Latent membrane protein 1 of Epstein–Barr virus interacts with JAK3 and activates STAT proteins
…, C Kaiser, R Zeidler, B Scheffer, M Ueffing… - The EMBO …, 1999 - embopress.org
Latent membrane protein 1 (LMP1) acts like a permanently activated receptor of the tumor
necrosis factor (TNF)‐receptor superfamily and is absolutely required for B cell …
necrosis factor (TNF)‐receptor superfamily and is absolutely required for B cell …
Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB
A Dumont, SP Hehner, TG Hofmann, M Ueffing… - Oncogene, 1999 - nature.com
Reactive oxygen species (ROS) play an important role in cell death induced by many different
stimuli. This study shows that hydrogen peroxide-induced apoptosis in T-cells did not …
stimuli. This study shows that hydrogen peroxide-induced apoptosis in T-cells did not …
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool
… 124 mm NaCl, 5 mm KCl, 2 mm MgCl 2 , 30 mm glucose, 25 mm HEPES, pH 7.4, and 2 mm …
or in Tyrode's solution containing 50 mm KCl or 2 μm TTX or 0.5 m sucrose. After fixation and …
or in Tyrode's solution containing 50 mm KCl or 2 μm TTX or 0.5 m sucrose. After fixation and …