Aim Internal sphincterotomy is the standard surgical treatment for chronic anal fissure, but is
frequently complicated by anal incontinence. Fissurectomy is proposed as an alternative …

Background Antibiotics are life-saving drugs but severely affect the gut microbiome with
short-term consequences including diarrhea and selection of antibiotic-resistant bacteria. Long-…

BACKGROUND/AIMS: This study aimed at correlating the presence of extrahepatic
manifestations with hepatitis B virus (HBV) genotypes in patients with chronic HBV infection. …

Chronic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to baboons
was shown previously to result in a motor syndrome and a pattern of striatal dopaminergic …

Aim The study aimed to evaluate outcome at 1 year of one‐ and two‐stage fistulotomy for
anal fistula in a large group of patients. Method A prospective multicentre observational study …

The progressive degeneration of dopamine neurons observed in idiopathic Parkinson's
disease was mimicked by injecting low doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (…

Background: Adherence is important for therapy of chronic diseases, but has still not been
well studied in real life in chronic hepatitis C. Aims: To assess adherence to hepatitis C …

The clinical significance of hepatitis B virus (HBV) genotypes is still under debate. The aims
of this study were to assess the distribution of HBV genotypes in France and to identify the …

… Marina Varastet , Marina Varastet … Cornely, Celine Feger, Aaron Dane, Marina Varastet,
Fabien Vitry, Jean de Gunzburg, Antoine Andremont, France Mentré, Mark H. Wilcox, An open …

AIM: To evaluate the impact of therapeutic education on adherence to antiviral treatment
and sustained virological response (SVR) in a real-life setting in genotype 2/3 hepatitis C, as …