Migraine: a complex genetic disorder

M Wessman, GM Terwindt, MA Kaunisto… - The Lancet …, 2007 - thelancet.com
Although family and twin studies show that there is a genetic component to migraine, no
genes predisposing to common forms of the disorder have been identified. The most …

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

…, MD Ferrari, AC Belin, M Dichgans, M Wessman… - Nature …, 2016 - nature.com
Migraine is a debilitating neurological disorder affecting around one in seven people worldwide,
but its molecular mechanisms remain poorly understood. There is some debate about …

Genome-wide meta-analysis identifies new susceptibility loci for migraine

…, M Dichgans, M Wessman… - Nature …, 2013 - nature.com
Migraine is the most common brain disorder, affecting approximately 14% of the adult
population, but its molecular mechanisms are poorly understood. We report the results of a meta-…

Genome-wide association analysis identifies susceptibility loci for migraine without aura

…, CM Van Duijn, J Kaprio, B Cormand, M Wessman… - Nature …, 2012 - nature.com
Migraine without aura is the most common form of migraine, characterized by recurrent
disabling headache and associated autonomic symptoms. To identify common genetic variants …

[HTML][HTML] WNT1 Mutations in Early-Onset Osteoporosis and Osteogenesis Imperfecta

…, JT Lu, M Pekkinen, M Wessman… - … England Journal of …, 2013 - Mass Medical Soc
<p id="p001">This report identifies human skeletal diseases associated with mutations in <italic>WNT1</italic>.
In 10 family members with dominantly inherited, early-onset osteoporosis…

[HTML][HTML] Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

…, OT Raitakari, GM Terwindt, M Kallela, M Wessman… - Nature …, 2022 - nature.com
Migraine affects over a billion individuals worldwide but its genetic underpinning remains
largely unknown. Here, we performed a genome-wide association study of 102,084 migraine …

Genetics of migraine

V Anttila, M Wessman, M Kallela, A Palotie - Handbook of clinical neurology, 2018 - Elsevier
… Author links open overlay panel Verneri Anttila 1 , Maija Wessman 2 , Mikko Kallela 3 , … a
large-scale family study reported a locus on 4q24 (Wessman et al., 2002). This was followed by …

Human CD34+ stem cells express the hiwigene, a human homologue of the Drosophila genepiwi

…, MC Nelson, JE Brandt, M Wessman… - Blood, The Journal …, 2001 - ashpublications.org
Hematopoietic stem cells (HSCs) are characterized by their dual abilities to undergo
differentiation into multiple hematopoietic cell lineages or to undergo self-renewal. The molecular …

Food neophobia shows heritable variation in humans

…, K Silventoinen, K Keskitalo, M Kallela, M Wessman… - Physiology & …, 2007 - Elsevier
Food neophobia refers to reluctance to eat unfamiliar foods. We determined the heritability
of food neophobia in a family and a twin sample. The family sample consisted of 28 Finnish …

[HTML][HTML] Sweet taste preferences are partly genetically determined: identification of a trait locus on chromosome 16

…, A Knaapila, M Kallela, A Palotie, M Wessman… - The American journal of …, 2007 - Elsevier
… Body mass index (in kg/m 2 ) ranged from 15.3 to 42.0 (x̄ ± SD: 26.0 ± 4.6). The study
protocol was approved by the Ethical Committee of Helsinki University Central Hospital. All …