Migraine: a complex genetic disorder
M Wessman, GM Terwindt, MA Kaunisto… - The Lancet …, 2007 - thelancet.com
Although family and twin studies show that there is a genetic component to migraine, no
genes predisposing to common forms of the disorder have been identified. The most …
genes predisposing to common forms of the disorder have been identified. The most …
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
…, MD Ferrari, AC Belin, M Dichgans, M Wessman… - Nature …, 2016 - nature.com
Migraine is a debilitating neurological disorder affecting around one in seven people worldwide,
but its molecular mechanisms remain poorly understood. There is some debate about …
but its molecular mechanisms remain poorly understood. There is some debate about …
Genome-wide meta-analysis identifies new susceptibility loci for migraine
…, M Dichgans, M Wessman… - Nature …, 2013 - nature.com
Migraine is the most common brain disorder, affecting approximately 14% of the adult
population, but its molecular mechanisms are poorly understood. We report the results of a meta-…
population, but its molecular mechanisms are poorly understood. We report the results of a meta-…
Genome-wide association analysis identifies susceptibility loci for migraine without aura
Migraine without aura is the most common form of migraine, characterized by recurrent
disabling headache and associated autonomic symptoms. To identify common genetic variants …
disabling headache and associated autonomic symptoms. To identify common genetic variants …
[HTML][HTML] WNT1 Mutations in Early-Onset Osteoporosis and Osteogenesis Imperfecta
…, JT Lu, M Pekkinen, M Wessman… - … England Journal of …, 2013 - Mass Medical Soc
<p id="p001">This report identifies human skeletal diseases associated with mutations in <italic>WNT1</italic>.
In 10 family members with dominantly inherited, early-onset osteoporosis…
In 10 family members with dominantly inherited, early-onset osteoporosis…
[HTML][HTML] Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
…, OT Raitakari, GM Terwindt, M Kallela, M Wessman… - Nature …, 2022 - nature.com
Migraine affects over a billion individuals worldwide but its genetic underpinning remains
largely unknown. Here, we performed a genome-wide association study of 102,084 migraine …
largely unknown. Here, we performed a genome-wide association study of 102,084 migraine …
Genetics of migraine
… Author links open overlay panel Verneri Anttila 1 , Maija Wessman 2 , Mikko Kallela 3 , … a
large-scale family study reported a locus on 4q24 (Wessman et al., 2002). This was followed by …
large-scale family study reported a locus on 4q24 (Wessman et al., 2002). This was followed by …
Human CD34+ stem cells express the hiwigene, a human homologue of the Drosophila genepiwi
…, MC Nelson, JE Brandt, M Wessman… - Blood, The Journal …, 2001 - ashpublications.org
Hematopoietic stem cells (HSCs) are characterized by their dual abilities to undergo
differentiation into multiple hematopoietic cell lineages or to undergo self-renewal. The molecular …
differentiation into multiple hematopoietic cell lineages or to undergo self-renewal. The molecular …
Food neophobia shows heritable variation in humans
…, K Silventoinen, K Keskitalo, M Kallela, M Wessman… - Physiology & …, 2007 - Elsevier
Food neophobia refers to reluctance to eat unfamiliar foods. We determined the heritability
of food neophobia in a family and a twin sample. The family sample consisted of 28 Finnish …
of food neophobia in a family and a twin sample. The family sample consisted of 28 Finnish …
[HTML][HTML] Sweet taste preferences are partly genetically determined: identification of a trait locus on chromosome 16
…, A Knaapila, M Kallela, A Palotie, M Wessman… - The American journal of …, 2007 - Elsevier
… Body mass index (in kg/m 2 ) ranged from 15.3 to 42.0 (x̄ ± SD: 26.0 ± 4.6). The study
protocol was approved by the Ethical Committee of Helsinki University Central Hospital. All …
protocol was approved by the Ethical Committee of Helsinki University Central Hospital. All …