User profiles for M.J. Meaney

Michael J Meaney

Singapore Institute for Clinical Sciences (A*STAR)
Verified email at mcgill.ca
Cited by 118759

Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress

…, S Sharma, D Pearson, PM Plotsky, MJ Meaney - Science, 1997 - science.org
Variations in maternal care affect the development of individual differences in neuroendocrine
responses to stress in rats. As adults, the offspring of mothers that exhibited more licking …

Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations

MJ Meaney - Annual review of neuroscience, 2001 - annualreviews.org
… The results of a recent study (F Champagne, J Diorio, MJ Meaney, unpublished data)
reflect the functional importance of such differences in oxytocin receptor levels. Thus, …

Socioeconomic status and the brain: mechanistic insights from human and animal research

DA Hackman, MJ Farah, MJ Meaney - Nature reviews neuroscience, 2010 - nature.com
Human brain development occurs within a socioeconomic context and childhood socioeconomic
status (SES) influences neural development — particularly of the systems that subserve …

Epigenetic programming by maternal behavior

…, JR Seckl, S Dymov, M Szyf, MJ Meaney - Nature …, 2004 - nature.com
Here we report that increased pup licking and grooming (LG) and arched-back nursing (ABN)
by rat mothers altered the offspring epigenome at a glucocorticoid receptor (GR) gene …

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

…, B Labonté, M Szyf, G Turecki, MJ Meaney - Nature …, 2009 - nature.com
Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through
epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse …

Nongenomic transmission across generations of maternal behavior and stress responses in the rat

D Francis, J Diorio, D Liu, MJ Meaney - Science, 1999 - science.org
In the rat, variations in maternal care appear to influence the development of behavioral and
endocrine responses to stress in the offspring. The results of cross-fostering studies …

[HTML][HTML] Brain charts for the human lifespan

…, SR Mathias, B Mazoyer, P McGuire, MJ Meaney… - Nature, 2022 - nature.com
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …

Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

PM Plotsky, MJ Meaney - Molecular brain research, 1993 - Elsevier
… and Meaney, MJ, Ontogeny and differential sensitivity to environmental factors of glucocorticoid
and mineralocorticoid receptors in the rat hippocampus, DeL,. Brain Res. 43 (1988) 158-…

Cortisol levels during human aging predict hippocampal atrophy and memory deficits

…, M Thakur, BS McEwen, RL Hauger, MJ Meaney - Nature …, 1998 - nature.com
Elevated glucocorticoid levels produce hippocampal dysfunction and correlate with individual
deficits in spatial learning in aged rats. Previously we related persistent cortisol increases …

Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat

…, D Francis, PM Plotsky, MJ Meaney - Proceedings of the …, 1998 - National Acad Sciences
The mothers of infant rats show individual differences in the frequency of licking/grooming
and arched-back nursing (LG-ABN) of pups that contribute to the development of individual …