Organs and organelles represent core biological systems in mammals, but the diversity in
protein composition remains unclear. Here, we combine subcellular fractionation with …

Early life experience is associated with long-term effects on behavior and epigenetic
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of both …

Understanding the tumor immune microenvironment (TIME) promises to be key for optimal
cancer therapy, especially in triple-negative breast cancer (TNBC). Integrating spatial …

Background: Massively parallel gene expression profiling has provided a more objective,
molecular-level characterization of breast cancer subtypes. Several bioinformatics tools are …

… Hallett conceived and designed the experiments. Michael T. Hallett provided the access
to breast cancer datasets. Mélanie Busby performed the experiments, analyzed the data and …

This paper develops a model for lateral gene transfer events (aka horizontal gene transfer
events) between a set of gene trees T 1 , T 2 , …, T k and a species tree S. To the best of our …

Immunosurveillance constitutes the first step of cancer immunoediting in which developing
malignant lesions are eliminated by antitumorigenic immune cells. However, the mechanisms …

… Michael T Hallett … Michael T Hallett … Scott MS, Thomas DY, Hallett MT (2004)
Predicting subcellular localization via protein motif co-occurrence. Genome Res 14: 1957–1966. …

We consider the problem of constructing a species tree given a number of gene trees. In the
frameworks introduced by Goodman et al. [3], Page [10], and Guigó, Muchnik, and Smith [5] …

The prediction of subcellular localization of proteins from their primary sequence is a challenging
problem in bioinformatics. We have created a Bayesian network localization predictor …